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N-Heterocyclic Carbene Capture by Cytochrome P450 3A4
Cytochrome P450 3A4 (CYP3A4) is the dominant P450 enzyme involved in human drug metabolism, and its inhibition may result in adverse interactions or, conversely, favorably reduce the systemic elimination rates of poorly bioavailable drugs. Herein we describe a spectroscopic investigation of the inte...
में बचाया:
| में प्रकाशित: | Mol Pharmacol |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931868/ https://ncbi.nlm.nih.gov/pubmed/27126611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103721 |
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