CtBP- an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors

Por Dcona, M. Michael, Morris, Benjamin L., Ellis, Keith C., Grossman, Steven R.
Publicado no Cancer Biol Ther (2017)

Phenylalanine-Based Inactivator of AKT Kinase: Design, Synthesis, and Biological Evaluation

Por Nguyen, Thuy, Coover, Robert A., Verghese, Jenson, Moran, Richard G., Ellis, Keith C.
Publicado em 2014

Enantiospecific synthesis and cytotoxicity of 7-(4-methoxyphenyl)-6-phenyl-2,3,8,8a-tetrahydroindolizin-5(1H)-one enantiomers

Por Kimball, F. Scott, Turunen, Brandon J., Ellis, Keith C., Himes, Richard H., Georg, Gunda I.
Publicado em 2008

Spin equilibrium and O(2)-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine–threonine dyad

Por Jennings, Gareth K., Modi, Anuja, Elenewski, Justin E., Ritchie, Caroline M., Nguyen, Thuy, Ellis, Keith C., Hackett, John C
Publicado em 2014

In Vivo and In Vitro Patterns of the Activity of Simocyclinone D8, an Angucyclinone Antibiotic from Streptomyces antibioticus

Por Oppegard, Lisa M., Hamann, Bree L., Streck, Kathryn R., Ellis, Keith C., Fiedler, Hans-Peter, Khodursky, Arkady B., Hiasa, Hiroshi
Publicado em 2009

Structure-guided design of a high affinity inhibitor to human CtBP

Por Hilbert, Brendan J., Morris, Benjamin L., Ellis, Keith C., Paulsen, Janet L., Schiffer, Celia A., Grossman, Steven R., Royer, William E.
Publicado no ACS Chem Biol (2015)

Transforming activity and therapeutic targeting of C-terminal Binding Protein 2 in Apc mutated neoplasia

Por Sumner, Evan T., Chawla, Ayesha T., Cororaton, Agnes D., Koblinski, Jennifer, Kovi, Ramesh C., Love, Ian M., Szomju, Barbara B., Korwar, Sudha, Ellis, Keith C., Grossman, Steven R.
Publicado no Oncogene (2017)

Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-Terminal Binding Protein (CtBP)

Por Korwar, Sudha, Morris, Benjamin L., Parikh, Hardik I., Coover, Robert A., Doughty, Tyler W., Love, Ian M., Hilbert, Brendan J., Royer, William E., Kellogg, Glen E., Grossman, Steven R., Ellis, Keith C.
Publicado no Bioorg Med Chem (2016)