Receptor Tyrosine Kinase-Mediated Angiogenesis

Por Jeltsch, Michael, Leppänen, Veli-Matti, Saharinen, Pipsa, Alitalo, Kari
Publicado em 2013

Substrate Efflux Propensity Is the Key Determinant of Ca(2+)-independent Phospholipase A-β (iPLAβ)-mediated Glycerophospholipid Hydrolysis

Por Batchu, Krishna Chaithanya, Hokynar, Kati, Jeltsch, Michael, Mattonet, Kenny, Somerharju, Pentti
Publicado no J Biol Chem (2015)

Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1

Por Jha, Sawan Kumar, Rauniyar, Khushbu, Karpanen, Terhi, Leppänen, Veli-Matti, Brouillard, Pascal, Vikkula, Miikka, Alitalo, Kari, Jeltsch, Michael
Publicado no Sci Rep (2017)

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

Por Achen, Marc G., Jeltsch, Michael, Kukk, Eola, Mäkinen, Taija, Vitali, Angela, Wilks, Andrew F., Alitalo, Kari, Stacker, Steven A.
Publicado em 1998

Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle

Por Anisimov, Andrey, Alitalo, Annamari, Korpisalo, Petra, Soronen, Jarkko, Kaijalainen, Seppo, Leppänen, Veli-Matti, Jeltsch, Michael, Ylä-Herttuala, Seppo, Alitalo, Kari
Publicado em 2009

A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development

Por Villefranc, Jacques A., Nicoli, Stefania, Bentley, Katie, Jeltsch, Michael, Zarkada, Georgia, Moore, John C., Gerhardt, Holger, Alitalo, Kari, Lawson, Nathan D.
Publicado em 2013

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

Por Gerhardt, Holger, Golding, Matthew, Fruttiger, Marcus, Ruhrberg, Christiana, Lundkvist, Andrea, Abramsson, Alexandra, Jeltsch, Michael, Mitchell, Christopher, Alitalo, Kari, Shima, David, Betsholtz, Christer
Publicado em 2003

Structural determinants of growth factor binding and specificity by VEGF receptor 2

Por Leppänen, Veli-Matti, Prota, Andrea E., Jeltsch, Michael, Anisimov, Andrey, Kalkkinen, Nisse, Strandin, Tomas, Lankinen, Hilkka, Goldman, Adrian, Ballmer-Hofer, Kurt, Alitalo, Kari
Publicado em 2010

Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells

Por Olofsson, Birgitta, Korpelainen, Eija, Pepper, Michael S., Mandriota, Stefano J., Aase, Karin, Kumar, Vijay, Gunji, Yuji, Jeltsch, Michael M., Shibuya, Masabumi, Alitalo, Kari, Eriksson, Ulf
Publicado em 1998

Functional Importance of a Proteoglycan Coreceptor in Pathologic Lymphangiogenesis

Por Johns, Scott C., Yin, Xin, Jeltsch, Michael, Bishop, Joseph R., Schuksz, Manuela, El Ghazal, Roland, Wilcox-Adelman, Sarah A., Alitalo, Kari, Fuster, Mark M.
Publicado no Circ Res (2016)

Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development

Por Saharinen, Pipsa, Helotera, Hanna, Miettinen, Juho, Norrmen, Camilla, D'Amico, Gabriela, Jeltsch, Michael, Langenberg, Tobias, Vandevelde, Wouter, Ny, Annelii, Dewerchin, Mieke, Carmeliet, Peter, Alitalo, Kari
Publicado em 2010

Suppressive Effects of Vascular Endothelial Growth Factor-B on Tumor Growth in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis

Por Albrecht, Imke, Kopfstein, Lucie, Strittmatter, Karin, Schomber, Tibor, Falkevall, Annelie, Hagberg, Carolina E., Lorentz, Pascal, Jeltsch, Michael, Alitalo, Kari, Eriksson, Ulf, Christofori, Gerhard, Pietras, Kristian
Publicado em 2010

Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation

Por Leppänen, Veli-Matti, Tvorogov, Denis, Kisko, Kaisa, Prota, Andrea E., Jeltsch, Michael, Anisimov, Andrey, Markovic-Mueller, Sandra, Stuttfeld, Edward, Goldie, Kenneth N., Ballmer-Hofer, Kurt, Alitalo, Kari
Publicado em 2013

Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice

Por Veikkola, Tanja, Jussila, Lotta, Makinen, Taija, Karpanen, Terhi, Jeltsch, Michael, Petrova, Tatiana V., Kubo, Hajime, Thurston, Gavin, McDonald, Donald M., Achen, Marc G., Stacker, Steven A., Alitalo, Kari
Publicado em 2001

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

Por Mandriota, Stefano J., Jussila, Lotta, Jeltsch, Michael, Compagni, Amelia, Baetens, Danielle, Prevo, Remko, Banerji, Suneale, Huarte, Joachim, Montesano, Roberto, Jackson, David G., Orci, Lelio, Alitalo, Kari, Christofori, Gerhard, Pepper, Michael S.
Publicado em 2001

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation

Por Baluk, Peter, Tammela, Tuomas, Ator, Erin, Lyubynska, Natalya, Achen, Marc G., Hicklin, Daniel J., Jeltsch, Michael, Petrova, Tatiana V., Pytowski, Bronislaw, Stacker, Steven A., Ylä-Herttuala, Seppo, Jackson, David G., Alitalo, Kari, McDonald, Donald M.
Publicado em 2005

Overexpression of VEGF-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy

Por Karpanen, Terhi, Bry, Maija, Ollila, Hanna M., Seppänen-Laakso, Tuulikki, Liimatta, Erkki, Leskinen, Hanna, Kivelä, Riikka, Helkamaa, Teemu, Merentie, Mari, Jeltsch, Michael, Paavonen, Karri, Andersson, Leif C., Mervaala, Eero, Hassinen, Ilmo E., Ylä-Herttuala, Seppo, Orešič, Matej, Alitalo, Kari
Publicado em 2008

Reevaluation of the Role of VEGF-B Suggests a Restricted Role in the Revascularization of the Ischemic Myocardium

Por Li, Xuri, Tjwa, Marc, Van Hove, Inge, Enholm, Berndt, Neven, Elke, Paavonen, Karri, Jeltsch, Michael, Juan, Toni Diez, Sievers, Richard E., Chorianopoulos, Emmanuel, Wada, Hiromichi, Vanwildemeersch, Maarten, Noel, Agnes, Foidart, Jean-Michel, Springer, Matthew L., von Degenfeld, Georges, Dewerchin, Mieke, Blau, Helen M., Alitalo, Kari, Eriksson, Ulf, Carmeliet, Peter, Moons, Lieve
Publicado em 2008