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Structural determinants of growth factor binding and specificity by VEGF receptor 2
Vascular endothelial growth factors (VEGFs) regulate blood and lymph vessel formation through activation of three receptor tyrosine kinases, VEGFR-1, -2, and -3. The extracellular domain of VEGF receptors consists of seven immunoglobulin homology domains, which, upon ligand binding, promote receptor...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823880/ https://ncbi.nlm.nih.gov/pubmed/20145116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914318107 |
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