VEGF-C protects the integrity of the bone marrow perivascular niche in mice

Hematopoietic stem cells (HSCs) reside in the bone marrow (BM) stem cell niche, which provides a vital source of HSC regulatory signals. Radiation and chemotherapy disrupt the HSC niche, including its sinusoidal vessels and perivascular cells, contributing to delayed hematopoietic recovery. Thus, id...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Fang, Shentong, Chen, Shuo, Nurmi, Harri, Leppänen, Veli-Matti, Jeltsch, Michael, Scadden, David, Silberstein, Lev, Mikkola, Hanna, Alitalo, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568034/
https://ncbi.nlm.nih.gov/pubmed/32842144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005699
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