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Substrate Efflux Propensity Is the Key Determinant of Ca(2+)-independent Phospholipase A-β (iPLAβ)-mediated Glycerophospholipid Hydrolysis
The A-type phospholipases (PLAs) are key players in glycerophospholipid (GPL) homeostasis and in mammalian cells; Ca(2+)-independent PLA-β (iPLAβ) in particular has been implicated in this essential process. However, the regulation of this enzyme, which is necessary to avoid futile competition betwe...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400325/ https://ncbi.nlm.nih.gov/pubmed/25713085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642835 |
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