Substrate Efflux Propensity Plays a Key Role in the Specificity of Secretory A-type Phospholipases

To better understand the principles underlying the substrate specificity of A-type phospholipases (PLAs), a high throughput mass spectrometric assay was employed to study the effect of acyl chain length and unsaturation of phospholipids on their rate of hydrolysis by three different secretory PLAs i...

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Bibliografske podrobnosti
Main Authors: Haimi, Perttu, Hermansson, Martin, Batchu, Krishna Chaithanya, Virtanen, Jorma A., Somerharju, Pentti
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804224/
https://ncbi.nlm.nih.gov/pubmed/19887372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061218
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