CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells

di Lee, Seung-Hee, Itkin-Ansari, Pamela, Levine, Fred
Pubblicazione 2010

Real-time Bioluminescence Imaging of Macroencapsulated Fibroblasts Reveals Allograft Protection in Rhesus Monkeys (Macaca mulatta)

di Tarantal, Alice F., Lee, C. Chang I., Itkin-Ansari, Pamela
Pubblicazione 2009

Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells

di Lee, Seung-Hee, Hao, Ergeng, Levine, Fred, Itkin-Ansari, Pamela
Pubblicazione 2011

HES6 REVERSES NUCLEAR REPROGRAMMING OF INSULIN-PRODUCING CELLS FOLLOWING CELL FUSION

di Ball, Andrew J., Abrahamsson, Annelie E., Tyrberg, Björn, Itkin-Ansari, Pamela, Levine, Fred
Pubblicazione 2007

Islet Specific Wnt Activation in Human Type II Diabetes

di Lee, Seung-Hee, Demeterco, Carla, Geron, Ifat, Abrahamsson, Annelie, Levine, Fred, Itkin-Ansari, Pamela
Pubblicazione 2008

Human β-cell Precursors Mature Into Functional Insulin-producing Cells in an Immunoisolation Device: Implications for Diabetes Cell Therapies

di Lee, Seung-Hee, Hao, Ergeng, Savinov, Alexei Y., Geron, Ifat, Strongin, Alex Y., Itkin-Ansari, Pamela
Pubblicazione 2009

Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release

di Pottekat, Anita, Becker, Scott, Spencer, Kathryn R., Yates, John R., Manning, Gerard, Itkin-Ansari, Pamela, Balch, William E.
Pubblicazione 2013

The Id3/E47 axis mediates cell cycle control in human pancreatic ducts and adenocarcinoma

di Lee, Seung-Hee, Hao, Ergeng, Kiselyuk, Alice, Shapiro, James, Shields, David J, Lowy, Andrew, Levine, Fred, Itkin-Ansari, Pamela
Pubblicazione 2011

Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment

di Jakubison, Brad L., Schweickert, Patrick G., Moser, Sarah E., Yang, Yi, Gao, Hongyu, Scully, Kathleen, Itkin‐Ansari, Pamela, Liu, Yunlong, Konieczny, Stephen F.
Pubblicato in Mol Oncol (2018)

A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer

di Villarino, Nicholas, Signaevskaia, Lia, van Niekerk, Jaco, Medal, Rachel, Kim, Heejung, Lahmy, Reyhaneh, Scully, Kathleen, Pinkerton, Anthony, Kim, Sangwun, Lowy, Andrew, Itkin-Ansari, Pamela
Pubblicato in Oncotarget (2017)

E47 Governs the MYC-CDKN1B/p27(KIP1)-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16(INK4A) and Wild-Type p53

di Scully, Kathleen M., Lahmy, Reyhaneh, Signaevskaia, Lia, Sasik, Roman, Medal, Rachel, Kim, Heejung, French, Randall, James, Brian, Wu, Yifan, Lowy, Andrew M., Itkin-Ansari, Pamela
Pubblicato in Cell Mol Gastroenterol Hepatol (2018)

Phenothiazine Neuroleptics Signal to the Human Insulin Promoter as Revealed by a Novel High-Throughput Screen

di KISELYUK, ALICE, FARBER-KATZ, SUZETTE, COHEN, TOM, LEE, SEUNG-HEE, GERON, IFAT, AZIMI, BEHRAD, HEYNEN-GENEL, SUSANNE, SINGER, ODED, PRICE, JEFFREY, MERCOLA, MARK, ITKIN-ANSARI, PAMELA, LEVINE, FRED
Pubblicazione 2010

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity

di Jang, Insook, Pottekat, Anita, Poothong, Juthakorn, Yong, Jing, Lagunas-Acosta, Jacqueline, Charbono, Adriana, Chen, Zhouji, Scheuner, Donalyn L, Liu, Ming, Itkin-Ansari, Pamela, Arvan, Peter, Kaufman, Randal J
Pubblicato in eLife (2019)

The Basic Helix-Loop-Helix Transcription Factor E47 Reprograms Human Pancreatic Cancer Cells to a Quiescent Acinar State With Reduced Tumorigenic Potential

di Kim, SangWun, Lahmy, Reyhaneh, Riha, Chelsea, Yang, Challeng, Jakubison, Brad L., van Niekerk, Jaco, Staub, Claudio, Wu, Yifan, Gates, Keith, Dong, Duc Si, Konieczny, Stephen F., Itkin-Ansari, Pamela
Pubblicato in Pancreas (2015)

Normal and defective pathways in biogenesis and maintenance of the insulin storage pool

di Liu, Ming, Huang, Yumeng, Xu, Xiaoxi, Li, Xin, Alam, Maroof, Arunagiri, Anoop, Haataja, Leena, Ding, Li, Wang, Shusen, Itkin-Ansari, Pamela, Kaufman, Randal J., Tsai, Billy, Qi, Ling, Arvan, Peter
Pubblicato in J Clin Invest (2021)

Proinsulin misfolding is an early event in the progression to type 2 diabetes

di Arunagiri, Anoop, Haataja, Leena, Pottekat, Anita, Pamenan, Fawnnie, Kim, Soohyun, Zeltser, Lori M, Paton, Adrienne W, Paton, James C, Tsai, Billy, Itkin-Ansari, Pamela, Kaufman, Randal J, Liu, Ming, Arvan, Peter
Pubblicato in eLife (2019)

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

di Tran, Duc T., Pottekat, Anita, Mir, Saiful A., Loguercio, Salvatore, Jang, Insook, Campos, Alexandre Rosa, Scully, Kathleen M., Lahmy, Reyhaneh, Liu, Ming, Arvan, Peter, Balch, William E., Kaufman, Randal J., Itkin-Ansari, Pamela
Pubblicato in Diabetes (2020)

Derivation of a Retinoid X Receptor Scaffold from Peroxisome Proliferator-Activated Receptor γ Ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene

di Dawson, Marcia I., Ye, Mao, Cao, Xihua, Farhana, Lulu, Hu, Qiong-Ying, Zhao, Yong, Xu, Li Ping, Kiselyuk, Alice, Correa, Ricardo G., Yang, Li, Hou, Tingjun, Reed, John C., Itkin-Ansari, Pamela, Levine, Fred, Sanner, Michel F., Fontana, Joseph A., Zhang, Xiao-Kun
Pubblicazione 2009

Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth

di Sun, Jinhong, Xiong, Yi, Li, Xin, Haataja, Leena, Chen, Wei, Mir, Saiful A., Lv, Li, Madley, Rachel, Larkin, Dennis, Anjum, Arfah, Dhayalan, Balamurugan, Rege, Nischay, Wickramasinghe, Nalinda P., Weiss, Michael A., Itkin-Ansari, Pamela, Kaufman, Randal J., Ostrov, David A., Arvan, Peter, Liu, Ming
Pubblicato in Diabetes (2020)

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

di Hassler, Justin R., Scheuner, Donalyn L., Wang, Shiyu, Han, Jaeseok, Kodali, Vamsi K., Li, Philip, Nguyen, Julie, George, Jenny S., Davis, Cory, Wu, Shengyang P., Bai, Yongsheng, Sartor, Maureen, Cavalcoli, James, Malhi, Harmeet, Baudouin, Gregory, Zhang, Yaoyang, Yates III, John R., Itkin-Ansari, Pamela, Volkmann, Niels, Kaufman, Randal J.
Pubblicato in PLoS Biol (2015)