טוען...
Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth
Abnormal interactions between misfolded mutant and wild-type (WT) proinsulin (PI) in the endoplasmic reticulum (ER) drive the molecular pathogenesis of mutant INS gene–induced diabetes of youth (MIDY). How these abnormal interactions are initiated remains unknown. Normally, PI-WT dimerizes in the ER...
שמור ב:
| הוצא לאור ב: | Diabetes |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Diabetes Association
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7171958/ https://ncbi.nlm.nih.gov/pubmed/32139596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-1106 |
| תגים: |
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