Normal and defective pathways in biogenesis and maintenance of the insulin storage pool

Both basal and glucose-stimulated insulin release occur primarily by insulin secretory granule exocytosis from pancreatic β cells, and both are needed to maintain normoglycemia. Loss of insulin-secreting β cells, accompanied by abnormal glucose tolerance, may involve simple exhaustion of insulin res...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Liu, Ming, Huang, Yumeng, Xu, Xiaoxi, Li, Xin, Alam, Maroof, Arunagiri, Anoop, Haataja, Leena, Ding, Li, Wang, Shusen, Itkin-Ansari, Pamela, Kaufman, Randal J., Tsai, Billy, Qi, Ling, Arvan, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2021
Teme:
Review Series
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810482/
https://ncbi.nlm.nih.gov/pubmed/33463547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI142240
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