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Biosynthesis, structure, and folding of the insulin precursor protein

Insulin synthesis in pancreatic beta cells is initiated as preproinsulin. Prevailing glucose concentrations, which oscillate pre- and post-prandially, exert major dynamic variation in preproinsulin biosynthesis. Accompanying upregulated translation of the insulin precursor include elements of the en...

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Detalhes bibliográficos
Publicado no:Diabetes Obes Metab
Main Authors: Liu, Ming, Weiss, Michael A., Arunagiri, Anoop, Yong, Jing, Rege, Nischay, Sun, Jinhong, Haataja, Leena, Kaufman, Randal J., Arvan, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463291/
https://ncbi.nlm.nih.gov/pubmed/30230185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13378
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