CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells

by Lee, Seung-Hee, Itkin-Ansari, Pamela, Levine, Fred
Published 2010

Real-time Bioluminescence Imaging of Macroencapsulated Fibroblasts Reveals Allograft Protection in Rhesus Monkeys (Macaca mulatta)

by Tarantal, Alice F., Lee, C. Chang I., Itkin-Ansari, Pamela
Published 2009

Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells

by Lee, Seung-Hee, Hao, Ergeng, Levine, Fred, Itkin-Ansari, Pamela
Published 2011

HES6 REVERSES NUCLEAR REPROGRAMMING OF INSULIN-PRODUCING CELLS FOLLOWING CELL FUSION

by Ball, Andrew J., Abrahamsson, Annelie E., Tyrberg, Björn, Itkin-Ansari, Pamela, Levine, Fred
Published 2007

Islet Specific Wnt Activation in Human Type II Diabetes

by Lee, Seung-Hee, Demeterco, Carla, Geron, Ifat, Abrahamsson, Annelie, Levine, Fred, Itkin-Ansari, Pamela
Published 2008

Human β-cell Precursors Mature Into Functional Insulin-producing Cells in an Immunoisolation Device: Implications for Diabetes Cell Therapies

by Lee, Seung-Hee, Hao, Ergeng, Savinov, Alexei Y., Geron, Ifat, Strongin, Alex Y., Itkin-Ansari, Pamela
Published 2009

Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release

by Pottekat, Anita, Becker, Scott, Spencer, Kathryn R., Yates, John R., Manning, Gerard, Itkin-Ansari, Pamela, Balch, William E.
Published 2013

The Id3/E47 axis mediates cell cycle control in human pancreatic ducts and adenocarcinoma

by Lee, Seung-Hee, Hao, Ergeng, Kiselyuk, Alice, Shapiro, James, Shields, David J, Lowy, Andrew, Levine, Fred, Itkin-Ansari, Pamela
Published 2011

Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment

by Jakubison, Brad L., Schweickert, Patrick G., Moser, Sarah E., Yang, Yi, Gao, Hongyu, Scully, Kathleen, Itkin‐Ansari, Pamela, Liu, Yunlong, Konieczny, Stephen F.
Published in Mol Oncol (2018)

A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer

by Villarino, Nicholas, Signaevskaia, Lia, van Niekerk, Jaco, Medal, Rachel, Kim, Heejung, Lahmy, Reyhaneh, Scully, Kathleen, Pinkerton, Anthony, Kim, Sangwun, Lowy, Andrew, Itkin-Ansari, Pamela
Published in Oncotarget (2017)

E47 Governs the MYC-CDKN1B/p27(KIP1)-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16(INK4A) and Wild-Type p53

by Scully, Kathleen M., Lahmy, Reyhaneh, Signaevskaia, Lia, Sasik, Roman, Medal, Rachel, Kim, Heejung, French, Randall, James, Brian, Wu, Yifan, Lowy, Andrew M., Itkin-Ansari, Pamela
Published in Cell Mol Gastroenterol Hepatol (2018)

Phenothiazine Neuroleptics Signal to the Human Insulin Promoter as Revealed by a Novel High-Throughput Screen

by KISELYUK, ALICE, FARBER-KATZ, SUZETTE, COHEN, TOM, LEE, SEUNG-HEE, GERON, IFAT, AZIMI, BEHRAD, HEYNEN-GENEL, SUSANNE, SINGER, ODED, PRICE, JEFFREY, MERCOLA, MARK, ITKIN-ANSARI, PAMELA, LEVINE, FRED
Published 2010

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity

by Jang, Insook, Pottekat, Anita, Poothong, Juthakorn, Yong, Jing, Lagunas-Acosta, Jacqueline, Charbono, Adriana, Chen, Zhouji, Scheuner, Donalyn L, Liu, Ming, Itkin-Ansari, Pamela, Arvan, Peter, Kaufman, Randal J
Published in eLife (2019)

The Basic Helix-Loop-Helix Transcription Factor E47 Reprograms Human Pancreatic Cancer Cells to a Quiescent Acinar State With Reduced Tumorigenic Potential

by Kim, SangWun, Lahmy, Reyhaneh, Riha, Chelsea, Yang, Challeng, Jakubison, Brad L., van Niekerk, Jaco, Staub, Claudio, Wu, Yifan, Gates, Keith, Dong, Duc Si, Konieczny, Stephen F., Itkin-Ansari, Pamela
Published in Pancreas (2015)

Normal and defective pathways in biogenesis and maintenance of the insulin storage pool

by Liu, Ming, Huang, Yumeng, Xu, Xiaoxi, Li, Xin, Alam, Maroof, Arunagiri, Anoop, Haataja, Leena, Ding, Li, Wang, Shusen, Itkin-Ansari, Pamela, Kaufman, Randal J., Tsai, Billy, Qi, Ling, Arvan, Peter
Published in J Clin Invest (2021)

Proinsulin misfolding is an early event in the progression to type 2 diabetes

by Arunagiri, Anoop, Haataja, Leena, Pottekat, Anita, Pamenan, Fawnnie, Kim, Soohyun, Zeltser, Lori M, Paton, Adrienne W, Paton, James C, Tsai, Billy, Itkin-Ansari, Pamela, Kaufman, Randal J, Liu, Ming, Arvan, Peter
Published in eLife (2019)

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

by Tran, Duc T., Pottekat, Anita, Mir, Saiful A., Loguercio, Salvatore, Jang, Insook, Campos, Alexandre Rosa, Scully, Kathleen M., Lahmy, Reyhaneh, Liu, Ming, Arvan, Peter, Balch, William E., Kaufman, Randal J., Itkin-Ansari, Pamela
Published in Diabetes (2020)

Derivation of a Retinoid X Receptor Scaffold from Peroxisome Proliferator-Activated Receptor γ Ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene

by Dawson, Marcia I., Ye, Mao, Cao, Xihua, Farhana, Lulu, Hu, Qiong-Ying, Zhao, Yong, Xu, Li Ping, Kiselyuk, Alice, Correa, Ricardo G., Yang, Li, Hou, Tingjun, Reed, John C., Itkin-Ansari, Pamela, Levine, Fred, Sanner, Michel F., Fontana, Joseph A., Zhang, Xiao-Kun
Published 2009

Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth

by Sun, Jinhong, Xiong, Yi, Li, Xin, Haataja, Leena, Chen, Wei, Mir, Saiful A., Lv, Li, Madley, Rachel, Larkin, Dennis, Anjum, Arfah, Dhayalan, Balamurugan, Rege, Nischay, Wickramasinghe, Nalinda P., Weiss, Michael A., Itkin-Ansari, Pamela, Kaufman, Randal J., Ostrov, David A., Arvan, Peter, Liu, Ming
Published in Diabetes (2020)

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

by Hassler, Justin R., Scheuner, Donalyn L., Wang, Shiyu, Han, Jaeseok, Kodali, Vamsi K., Li, Philip, Nguyen, Julie, George, Jenny S., Davis, Cory, Wu, Shengyang P., Bai, Yongsheng, Sartor, Maureen, Cavalcoli, James, Malhi, Harmeet, Baudouin, Gregory, Zhang, Yaoyang, Yates III, John R., Itkin-Ansari, Pamela, Volkmann, Niels, Kaufman, Randal J.
Published in PLoS Biol (2015)