CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells

par Lee, Seung-Hee, Itkin-Ansari, Pamela, Levine, Fred
Publié 2010

Real-time Bioluminescence Imaging of Macroencapsulated Fibroblasts Reveals Allograft Protection in Rhesus Monkeys (Macaca mulatta)

par Tarantal, Alice F., Lee, C. Chang I., Itkin-Ansari, Pamela
Publié 2009

Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells

par Lee, Seung-Hee, Hao, Ergeng, Levine, Fred, Itkin-Ansari, Pamela
Publié 2011

HES6 REVERSES NUCLEAR REPROGRAMMING OF INSULIN-PRODUCING CELLS FOLLOWING CELL FUSION

par Ball, Andrew J., Abrahamsson, Annelie E., Tyrberg, Björn, Itkin-Ansari, Pamela, Levine, Fred
Publié 2007

Islet Specific Wnt Activation in Human Type II Diabetes

par Lee, Seung-Hee, Demeterco, Carla, Geron, Ifat, Abrahamsson, Annelie, Levine, Fred, Itkin-Ansari, Pamela
Publié 2008

Human β-cell Precursors Mature Into Functional Insulin-producing Cells in an Immunoisolation Device: Implications for Diabetes Cell Therapies

par Lee, Seung-Hee, Hao, Ergeng, Savinov, Alexei Y., Geron, Ifat, Strongin, Alex Y., Itkin-Ansari, Pamela
Publié 2009

Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release

par Pottekat, Anita, Becker, Scott, Spencer, Kathryn R., Yates, John R., Manning, Gerard, Itkin-Ansari, Pamela, Balch, William E.
Publié 2013

The Id3/E47 axis mediates cell cycle control in human pancreatic ducts and adenocarcinoma

par Lee, Seung-Hee, Hao, Ergeng, Kiselyuk, Alice, Shapiro, James, Shields, David J, Lowy, Andrew, Levine, Fred, Itkin-Ansari, Pamela
Publié 2011

Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment

par Jakubison, Brad L., Schweickert, Patrick G., Moser, Sarah E., Yang, Yi, Gao, Hongyu, Scully, Kathleen, Itkin‐Ansari, Pamela, Liu, Yunlong, Konieczny, Stephen F.
Publié dans Mol Oncol (2018)

A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer

par Villarino, Nicholas, Signaevskaia, Lia, van Niekerk, Jaco, Medal, Rachel, Kim, Heejung, Lahmy, Reyhaneh, Scully, Kathleen, Pinkerton, Anthony, Kim, Sangwun, Lowy, Andrew, Itkin-Ansari, Pamela
Publié dans Oncotarget (2017)

E47 Governs the MYC-CDKN1B/p27(KIP1)-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16(INK4A) and Wild-Type p53

par Scully, Kathleen M., Lahmy, Reyhaneh, Signaevskaia, Lia, Sasik, Roman, Medal, Rachel, Kim, Heejung, French, Randall, James, Brian, Wu, Yifan, Lowy, Andrew M., Itkin-Ansari, Pamela
Publié dans Cell Mol Gastroenterol Hepatol (2018)

Phenothiazine Neuroleptics Signal to the Human Insulin Promoter as Revealed by a Novel High-Throughput Screen

par KISELYUK, ALICE, FARBER-KATZ, SUZETTE, COHEN, TOM, LEE, SEUNG-HEE, GERON, IFAT, AZIMI, BEHRAD, HEYNEN-GENEL, SUSANNE, SINGER, ODED, PRICE, JEFFREY, MERCOLA, MARK, ITKIN-ANSARI, PAMELA, LEVINE, FRED
Publié 2010

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity

par Jang, Insook, Pottekat, Anita, Poothong, Juthakorn, Yong, Jing, Lagunas-Acosta, Jacqueline, Charbono, Adriana, Chen, Zhouji, Scheuner, Donalyn L, Liu, Ming, Itkin-Ansari, Pamela, Arvan, Peter, Kaufman, Randal J
Publié dans eLife (2019)

The Basic Helix-Loop-Helix Transcription Factor E47 Reprograms Human Pancreatic Cancer Cells to a Quiescent Acinar State With Reduced Tumorigenic Potential

par Kim, SangWun, Lahmy, Reyhaneh, Riha, Chelsea, Yang, Challeng, Jakubison, Brad L., van Niekerk, Jaco, Staub, Claudio, Wu, Yifan, Gates, Keith, Dong, Duc Si, Konieczny, Stephen F., Itkin-Ansari, Pamela
Publié dans Pancreas (2015)

Normal and defective pathways in biogenesis and maintenance of the insulin storage pool

par Liu, Ming, Huang, Yumeng, Xu, Xiaoxi, Li, Xin, Alam, Maroof, Arunagiri, Anoop, Haataja, Leena, Ding, Li, Wang, Shusen, Itkin-Ansari, Pamela, Kaufman, Randal J., Tsai, Billy, Qi, Ling, Arvan, Peter
Publié dans J Clin Invest (2021)

Proinsulin misfolding is an early event in the progression to type 2 diabetes

par Arunagiri, Anoop, Haataja, Leena, Pottekat, Anita, Pamenan, Fawnnie, Kim, Soohyun, Zeltser, Lori M, Paton, Adrienne W, Paton, James C, Tsai, Billy, Itkin-Ansari, Pamela, Kaufman, Randal J, Liu, Ming, Arvan, Peter
Publié dans eLife (2019)

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

par Tran, Duc T., Pottekat, Anita, Mir, Saiful A., Loguercio, Salvatore, Jang, Insook, Campos, Alexandre Rosa, Scully, Kathleen M., Lahmy, Reyhaneh, Liu, Ming, Arvan, Peter, Balch, William E., Kaufman, Randal J., Itkin-Ansari, Pamela
Publié dans Diabetes (2020)

Derivation of a Retinoid X Receptor Scaffold from Peroxisome Proliferator-Activated Receptor γ Ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene

par Dawson, Marcia I., Ye, Mao, Cao, Xihua, Farhana, Lulu, Hu, Qiong-Ying, Zhao, Yong, Xu, Li Ping, Kiselyuk, Alice, Correa, Ricardo G., Yang, Li, Hou, Tingjun, Reed, John C., Itkin-Ansari, Pamela, Levine, Fred, Sanner, Michel F., Fontana, Joseph A., Zhang, Xiao-Kun
Publié 2009

Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth

par Sun, Jinhong, Xiong, Yi, Li, Xin, Haataja, Leena, Chen, Wei, Mir, Saiful A., Lv, Li, Madley, Rachel, Larkin, Dennis, Anjum, Arfah, Dhayalan, Balamurugan, Rege, Nischay, Wickramasinghe, Nalinda P., Weiss, Michael A., Itkin-Ansari, Pamela, Kaufman, Randal J., Ostrov, David A., Arvan, Peter, Liu, Ming
Publié dans Diabetes (2020)

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

par Hassler, Justin R., Scheuner, Donalyn L., Wang, Shiyu, Han, Jaeseok, Kodali, Vamsi K., Li, Philip, Nguyen, Julie, George, Jenny S., Davis, Cory, Wu, Shengyang P., Bai, Yongsheng, Sartor, Maureen, Cavalcoli, James, Malhi, Harmeet, Baudouin, Gregory, Zhang, Yaoyang, Yates III, John R., Itkin-Ansari, Pamela, Volkmann, Niels, Kaufman, Randal J.
Publié dans PLoS Biol (2015)