CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells

بواسطة Lee, Seung-Hee, Itkin-Ansari, Pamela, Levine, Fred
منشور في 2010

Real-time Bioluminescence Imaging of Macroencapsulated Fibroblasts Reveals Allograft Protection in Rhesus Monkeys (Macaca mulatta)

بواسطة Tarantal, Alice F., Lee, C. Chang I., Itkin-Ansari, Pamela
منشور في 2009

Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells

بواسطة Lee, Seung-Hee, Hao, Ergeng, Levine, Fred, Itkin-Ansari, Pamela
منشور في 2011

HES6 REVERSES NUCLEAR REPROGRAMMING OF INSULIN-PRODUCING CELLS FOLLOWING CELL FUSION

بواسطة Ball, Andrew J., Abrahamsson, Annelie E., Tyrberg, Björn, Itkin-Ansari, Pamela, Levine, Fred
منشور في 2007

Islet Specific Wnt Activation in Human Type II Diabetes

بواسطة Lee, Seung-Hee, Demeterco, Carla, Geron, Ifat, Abrahamsson, Annelie, Levine, Fred, Itkin-Ansari, Pamela
منشور في 2008

Human β-cell Precursors Mature Into Functional Insulin-producing Cells in an Immunoisolation Device: Implications for Diabetes Cell Therapies

بواسطة Lee, Seung-Hee, Hao, Ergeng, Savinov, Alexei Y., Geron, Ifat, Strongin, Alex Y., Itkin-Ansari, Pamela
منشور في 2009

Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release

بواسطة Pottekat, Anita, Becker, Scott, Spencer, Kathryn R., Yates, John R., Manning, Gerard, Itkin-Ansari, Pamela, Balch, William E.
منشور في 2013

The Id3/E47 axis mediates cell cycle control in human pancreatic ducts and adenocarcinoma

بواسطة Lee, Seung-Hee, Hao, Ergeng, Kiselyuk, Alice, Shapiro, James, Shields, David J, Lowy, Andrew, Levine, Fred, Itkin-Ansari, Pamela
منشور في 2011

Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment

بواسطة Jakubison, Brad L., Schweickert, Patrick G., Moser, Sarah E., Yang, Yi, Gao, Hongyu, Scully, Kathleen, Itkin‐Ansari, Pamela, Liu, Yunlong, Konieczny, Stephen F.
الحاوية / القاعدة Mol Oncol (2018)

A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer

بواسطة Villarino, Nicholas, Signaevskaia, Lia, van Niekerk, Jaco, Medal, Rachel, Kim, Heejung, Lahmy, Reyhaneh, Scully, Kathleen, Pinkerton, Anthony, Kim, Sangwun, Lowy, Andrew, Itkin-Ansari, Pamela
الحاوية / القاعدة Oncotarget (2017)

E47 Governs the MYC-CDKN1B/p27(KIP1)-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16(INK4A) and Wild-Type p53

بواسطة Scully, Kathleen M., Lahmy, Reyhaneh, Signaevskaia, Lia, Sasik, Roman, Medal, Rachel, Kim, Heejung, French, Randall, James, Brian, Wu, Yifan, Lowy, Andrew M., Itkin-Ansari, Pamela
الحاوية / القاعدة Cell Mol Gastroenterol Hepatol (2018)

Phenothiazine Neuroleptics Signal to the Human Insulin Promoter as Revealed by a Novel High-Throughput Screen

بواسطة KISELYUK, ALICE, FARBER-KATZ, SUZETTE, COHEN, TOM, LEE, SEUNG-HEE, GERON, IFAT, AZIMI, BEHRAD, HEYNEN-GENEL, SUSANNE, SINGER, ODED, PRICE, JEFFREY, MERCOLA, MARK, ITKIN-ANSARI, PAMELA, LEVINE, FRED
منشور في 2010

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity

بواسطة Jang, Insook, Pottekat, Anita, Poothong, Juthakorn, Yong, Jing, Lagunas-Acosta, Jacqueline, Charbono, Adriana, Chen, Zhouji, Scheuner, Donalyn L, Liu, Ming, Itkin-Ansari, Pamela, Arvan, Peter, Kaufman, Randal J
الحاوية / القاعدة eLife (2019)

The Basic Helix-Loop-Helix Transcription Factor E47 Reprograms Human Pancreatic Cancer Cells to a Quiescent Acinar State With Reduced Tumorigenic Potential

بواسطة Kim, SangWun, Lahmy, Reyhaneh, Riha, Chelsea, Yang, Challeng, Jakubison, Brad L., van Niekerk, Jaco, Staub, Claudio, Wu, Yifan, Gates, Keith, Dong, Duc Si, Konieczny, Stephen F., Itkin-Ansari, Pamela
الحاوية / القاعدة Pancreas (2015)

Normal and defective pathways in biogenesis and maintenance of the insulin storage pool

بواسطة Liu, Ming, Huang, Yumeng, Xu, Xiaoxi, Li, Xin, Alam, Maroof, Arunagiri, Anoop, Haataja, Leena, Ding, Li, Wang, Shusen, Itkin-Ansari, Pamela, Kaufman, Randal J., Tsai, Billy, Qi, Ling, Arvan, Peter
الحاوية / القاعدة J Clin Invest (2021)

Proinsulin misfolding is an early event in the progression to type 2 diabetes

بواسطة Arunagiri, Anoop, Haataja, Leena, Pottekat, Anita, Pamenan, Fawnnie, Kim, Soohyun, Zeltser, Lori M, Paton, Adrienne W, Paton, James C, Tsai, Billy, Itkin-Ansari, Pamela, Kaufman, Randal J, Liu, Ming, Arvan, Peter
الحاوية / القاعدة eLife (2019)

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

بواسطة Tran, Duc T., Pottekat, Anita, Mir, Saiful A., Loguercio, Salvatore, Jang, Insook, Campos, Alexandre Rosa, Scully, Kathleen M., Lahmy, Reyhaneh, Liu, Ming, Arvan, Peter, Balch, William E., Kaufman, Randal J., Itkin-Ansari, Pamela
الحاوية / القاعدة Diabetes (2020)

Derivation of a Retinoid X Receptor Scaffold from Peroxisome Proliferator-Activated Receptor γ Ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene

بواسطة Dawson, Marcia I., Ye, Mao, Cao, Xihua, Farhana, Lulu, Hu, Qiong-Ying, Zhao, Yong, Xu, Li Ping, Kiselyuk, Alice, Correa, Ricardo G., Yang, Li, Hou, Tingjun, Reed, John C., Itkin-Ansari, Pamela, Levine, Fred, Sanner, Michel F., Fontana, Joseph A., Zhang, Xiao-Kun
منشور في 2009

Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth

بواسطة Sun, Jinhong, Xiong, Yi, Li, Xin, Haataja, Leena, Chen, Wei, Mir, Saiful A., Lv, Li, Madley, Rachel, Larkin, Dennis, Anjum, Arfah, Dhayalan, Balamurugan, Rege, Nischay, Wickramasinghe, Nalinda P., Weiss, Michael A., Itkin-Ansari, Pamela, Kaufman, Randal J., Ostrov, David A., Arvan, Peter, Liu, Ming
الحاوية / القاعدة Diabetes (2020)

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

بواسطة Hassler, Justin R., Scheuner, Donalyn L., Wang, Shiyu, Han, Jaeseok, Kodali, Vamsi K., Li, Philip, Nguyen, Julie, George, Jenny S., Davis, Cory, Wu, Shengyang P., Bai, Yongsheng, Sartor, Maureen, Cavalcoli, James, Malhi, Harmeet, Baudouin, Gregory, Zhang, Yaoyang, Yates III, John R., Itkin-Ansari, Pamela, Volkmann, Niels, Kaufman, Randal J.
الحاوية / القاعدة PLoS Biol (2015)