The potential for BRAF V600 inhibitors in advanced cutaneous melanoma: rationale and latest evidence

Por Lemech, Charlotte, Infante, Jeffrey, Arkenau, Hendrik-Tobias
Publicado em 2012

Clinical Impact of Checkpoint Inhibitors as Novel Cancer Therapies

Por Shih, Kent, Arkenau, Hendrik-Tobias, Infante, Jeffrey R.
Publicado no Drugs (2014)

Evaluation of CYP3A‐mediated drug–drug interactions with romidepsin in patients with advanced cancer

Por Laille, Eric, Patel, Manish, Jones, Suzanne F., Burris, Howard A., Infante, Jeffrey, Lemech, Charlotte, Liu, Liangang, Arkenau, Hendrik‐Tobias
Publicado no J Clin Pharmacol (2015)

A Phase I Study of Weekly Topotecan in Combination with Pemetrexed in Patients with Advanced Malignancies

Por Burris, Howard A., Infante, Jeffrey R., Jewell, Roxanne C., Spigel, David R., Greco, F. Anthony, Thompson, Dana S., Jones, Suzanne F.
Publicado em 2010

ASP9853, an inhibitor of inducible nitric oxide synthase dimerization, in combination with docetaxel: Preclinical investigation and a Phase I study in advanced solid tumors

Por Luke, Jason J., LoRusso, Patricia, Shapiro, Geoffrey I., Krivoshik, Andrew, Schuster, Robin, Yamazaki, Takao, Arai, Yukinori, Fakhoury, Allam, Dmuchowski, Carl, Infante, Jeffrey R.
Publicado no Cancer Chemother Pharmacol (2016)

Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer

Por Bendell, Johanna C., Rosen, Lee S., Mayer, Robert J., Goldman, Jonathan W., Infante, Jeffrey R., Benedetti, Fabio, Lin, Donghu, Mizuguchi, Hirokazu, Zergebel, Christopher, Patel, Manish R.
Publicado no Cancer Chemother Pharmacol (2015)

Erratum to: Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer

Por Bendell, Johanna C., Rosen, Lee S., Mayer, Robert J., Goldman, Jonathan W., Infante, Jeffrey R., Benedetti, Fabio, Lin, Donghu, Mizuguchi, Hirokazu, Zergebel, Christopher, Patel, Manish R.
Publicado no Cancer Chemother Pharmacol (2015)

A phase I dose-escalation study of selumetinib in combination with docetaxel or dacarbazine in patients with advanced solid tumors

Por LoRusso, Patricia M., Infante, Jeffrey R., Kim, Kevin B., Burris, Howard A., Curt, Gregory, Emeribe, Ugochi, Clemett, Delyth, Tomkinson, Helen K., Cohen, Roger B.
Publicado no BMC Cancer (2017)

A first-in-human dose-escalation study of ME-143, a second generation NADH oxidase inhibitor, in patients with advanced solid tumors

Por Pant, Shubham, Burris, Howard A., Moore, Kathleen, Bendell, Johanna C., Kurkjian, Carla, Jones, Suzanne F., Moreno, Ofir, Kuhn, John G., McMeekin, Scott, Infante, Jeffrey R.
Publicado em 2013

New Markers of Pancreatic Cancer Identified Through Differential Gene Expression Analyses: Claudin 18 and Annexin A8

Por Karanjawala, Zarir E., Illei, Peter B., Ashfaq, Raheela, Infante, Jeffrey R., Murphy, Kathleen, Pandey, Akhilesh, Schulick, Richard, Winter, Jordan, Sharma, Rajni, Maitra, Anirban, Goggins, Michael, Hruban, Ralph H.
Publicado em 2008

Lenalidomide in combination with gemcitabine as first-line treatment for patients with metastatic carcinoma of the pancreas: A Sarah Cannon Research Institute phase II trial

Por Infante, Jeffrey R., Arkenau, Hendrik-Tobias, Bendell, Johanna C., Rubin, Mark S., Waterhouse, David, Jones, George Tripp, Spigel, David R., Lane, Cassie M., Hainsworth, John D., Burris III, Howard A.
Publicado em 2013

Phase 1, Open-Label, Dose Escalation, Safety, and Pharmacokinetics Study of ME-344 as a Single Agent in Patients With Refractory Solid Tumors

Por Bendell, Johanna C, Patel, Manish R, Infante, Jeffrey R, Kurkjian, Carla D, Jones, Suzanne F, Pant, Shubham, Burris, Howard A, Moreno, Ofir, Esquibel, Vanessa, Levin, Wendy, Moore, Kathleen N
Publicado no Cancer (2015)

Prognostic Factors of Survival in a Randomized Phase III Trial (MPACT) of Weekly nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone in Patients With Metastatic Pancreatic Can...

Por Tabernero, Josep, Chiorean, E. Gabriela, Infante, Jeffrey R., Hingorani, Sunil R., Ganju, Vinod, Weekes, Colin, Scheithauer, Werner, Ramanathan, Ramesh K., Goldstein, David, Penenberg, Darryl N., Romano, Alfredo, Ferrara, Stefano, Von Hoff, Daniel D.
Publicado no Oncologist (2015)

A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors

Por Heath, Elisabeth I., Infante, Jeffrey, Lewis, Lionel D., Luu, Thehang, Stephenson, Joe, Tan, Antoinette R., Kasubhai, Saifuddin, LoRusso, Patricia, Ma, Bo, Suttle, A. Benjamin, Kleha, Joseph F., Ball, Howard A., Dar, Mohammed M.
Publicado em 2013

Phase I Study of Pazopanib in Combination with Weekly Paclitaxel in Patients with Advanced Solid Tumors

Por Tan, Antoinette R., Dowlati, Afshin, Jones, Suzanne F., Infante, Jeffrey R., Nishioka, Jennifer, Fang, Lei, Hodge, Jeffrey P., Gainer, Shelby D., Arumugham, Thangam, Suttle, A. Benjamin, Dar, Mohammed M., Lager, Joanne J., Burris, Howard A.
Publicado em 2010

Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors

Por Wu, Huali, Infante, Jeffrey R, Keedy, Vicki L, Jones, Suzanne F, Chan, Emily, Bendell, Johanna C, Lee, Wooin, Kirschbrown, Whitney P, Zamboni, Beth A, Ikeda, Satoshi, Kodaira, Hiroshi, Rothenberg, Mace L, Burris, Howard A, Zamboni, William C
Publicado no Int J Nanomedicine (2015)

Phase I Study of LY2606368, a Checkpoint Kinase 1 Inhibitor, in Patients With Advanced Cancer

Por Hong, David, Infante, Jeffrey, Janku, Filip, Jones, Suzanne, Nguyen, Ly M., Burris, Howard, Naing, Aung, Bauer, Todd M., Piha-Paul, Sarina, Johnson, Faye M., Kurzrock, Razelle, Golden, Lisa, Hynes, Scott, Lin, Ji, Lin, Aimee Bence, Bendell, Johanna
Publicado no J Clin Oncol (2016)

Phase 1 study of MLN8054, a selective inhibitor of Aurora A kinase in patients with advanced solid tumors

Por Dees, E. Claire, Infante, Jeffrey R., Cohen, Roger B., O’Neil, Bert H., Jones, Suzanne, von Mehren, Margaret, Danaee, Hadi, Lee, Yih, Ecsedy, Jeffrey, Manfredi, Mark, Galvin, Katherine, Stringer, Bradley, Liu, Hua, Eton, Omar, Fingert, Howard, Burris, Howard
Publicado em 2010

Accumulation of Extracellular Hyaluronan by Hyaluronan Synthase 3 Promotes Tumor Growth and Modulates the Pancreatic Cancer Microenvironment

Por Kultti, Anne, Zhao, Chunmei, Singha, Netai C., Zimmerman, Susan, Osgood, Ryan J., Symons, Rebecca, Jiang, Ping, Li, Xiaoming, Thompson, Curtis B., Infante, Jeffrey R., Jacobetz, Michael A., Tuveson, David A., Frost, Gregory I., Shepard, H. Michael, Huang, Zhongdong
Publicado em 2014

CD8+ T cell stimulation with pegylated recombinant human IL-10 in the patient with advanced solid tumors - a Phase I study

Por Naing, Aung, Infante, Jeffrey R, Papadopoulos, Kyriakos P, Autio, Karen A, Wong, Deborah J, Falchook, Gerald S, Patel, Manish R, Pant, Shubham, Whiteside, Melinda, Bendell, Johanna, Bauer, Todd M, Janku, Filip, Javle, Milind, Colen, Rivka, Tannir, Nizar, Oft, Martin
Publicado no J Immunother Cancer (2015)