Pharmacogenomic diversity of tamoxifen metabolites and estrogen receptor genes in Hispanics and non-Hispanic whites with breast cancer

Por Rangel, Leticia B. A., Taraba, Jodi L., Frei, Christopher R., Smith, Lon, Rodriguez, Gladys, Kuhn, John G.
Publicado no Breast Cancer Res Treat (2014)

A first-in-human dose-escalation study of ME-143, a second generation NADH oxidase inhibitor, in patients with advanced solid tumors

Por Pant, Shubham, Burris, Howard A., Moore, Kathleen, Bendell, Johanna C., Kurkjian, Carla, Jones, Suzanne F., Moreno, Ofir, Kuhn, John G., McMeekin, Scott, Infante, Jeffrey R.
Publicado em 2013

A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03

Por Iwamoto, Fabio M., Lamborn, Kathleen R., Kuhn, John G., Wen, Patrick Y., Alfred Yung, W.K., Gilbert, Mark R., Chang, Susan M., Lieberman, Frank S., Prados, Michael D., Fine, Howard A.
Publicado em 2011

Fungal Metabolite Ophiobolin A as a Promising Anti-Glioma Agent: In Vivo Evaluation, Structure-Activity Relationship and Unique Pyrrolylation of Primary Amines

Por Dasari, Ramesh, Masi, Marco, Lisy, Romana, Ferdérin,c, Marlène, English, Lance R., Cimino, Alessio, Mathieu, Véronique, Brenner, Andrew J., Kuhn, John G., Whitten, Steven T., Evidente, Antonio, Kiss, Robert, Kornienko, Alexander
Publicado no Bioorg Med Chem Lett (2015)

A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study.

Por Robins, H. Ian, Chang, Susan M., Prados, Michael D., Yung, W. K. Alfred, Hess, Kenneth, Schiff, David, Greenberg, Harry, Fink, Karen, Nicolas, Kelly, Kuhn, John G., Cloughesy, Timothy, Junck, Larry, Mehta, Minesh
Publicado em 2002

Metformin for Reducing Racial/Ethnic Difference in Prostate Cancer Incidence for Men with Type 2 Diabetes

Por Wang, Chen-Pin, Lehman, Donna M., Lam, Yui-Wing F., Kuhn, John G., Mahalingam, Devalingam, Weitman, Steven, Lorenzo, Carlos, Downs, John R., Stuart, Elizabeth A, Hernandez, Javier, Thompson, Ian M., Ramirez, Amelie G.
Publicado no Cancer Prev Res (Phila) (2016)

Pharmacokinetic and Tumor Distribution Characteristics of Temsirolimus in Patients with Recurrent Malignant Glioma

Por Kuhn, John G., Chang, Susan M., Wen, Patrick Y., Cloughesy, Timothy F., Greenberg, Harry, Schiff, David, Conrad, Charles, Fink, Karen L., Robins, H. Ian, Mehta, Minesh, DeAngelis, Lisa, Raizer, Jeffrey, Hess, Kenneth, Lamborn, Kathleen R., Dancey, Janet, Prados, Michael D.
Publicado no Clin Cancer Res (2007)

Neurooncology clinical trial design for targeted therapies: Lessons learned from the North American Brain Tumor Consortium

Por Chang, Susan M., Lamborn, Kathleen R., Kuhn, John G., Yung, W.K. Alfred, Gilbert, Mark R., Wen, Patrick Y., Fine, Howard A., Mehta, Minesh P., DeAngelis, Lisa M., Lieberman, Frank S., Cloughesy, Timothy F., Robins, H. Ian, Abrey, Lauren E., Prados, Michael D.
Publicado em 2008

Is surgery at progression a prognostic marker for improved 6-month progression-free survival or overall survival for patients with recurrent glioblastoma?

Por Clarke†, Jennifer L., Ennis†, Michele M., Yung, W. K. Alfred, Chang, Susan M., Wen, Patrick Y., Cloughesy, Timothy F., DeAngelis, Lisa M., Robins, H. Ian, Lieberman, Frank S., Fine, Howard A., Abrey, Lauren, Gilbert, Mark R., Mehta, Minesh, Kuhn, John G., Aldape, Kenneth D., Lamborn, Kathleen R., Prados, Michael D.
Publicado em 2011

A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy(†)

Por Raizer, Jeffrey J., Abrey, Lauren E., Lassman, Andrew B., Chang, Susan M., Lamborn, Kathleen R., Kuhn, John G., Yung, W.K. Alfred, Gilbert, Mark R., Aldape, Kenneth A., Wen, Patrick Y., Fine, Howard A., Mehta, Minesh, DeAngelis, Lisa M., Lieberman, Frank, Cloughesy, Timothy F., Robins, H. Ian, Dancey, Janet, Prados, Michael D.
Publicado em 2010

A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas(†)

Por Raizer, Jeffrey J., Abrey, Lauren E., Lassman, Andrew B., Chang, Susan M., Lamborn, Kathleen R., Kuhn, John G., Yung, W.K. Alfred, Gilbert, Mark R., Aldape, Kenneth D., Wen, Patrick Y., Fine, Howard A., Mehta, Minesh, DeAngelis, Lisa M., Lieberman, Frank, Cloughesy, Timothy F., Robins, H. Ian, Dancey, Janet, Prados, Michael D.
Publicado em 2010

Phase II Study of Fenretinide (NSC 374551) in Adults With Recurrent Malignant Gliomas: A North American Brain Tumor Consortium Study

Por Puduvalli, Vinay K., Yung, W.K. Alfred, Hess, Kenneth R., Kuhn, John G., Groves, Morris D., Levin, Victor A., Zwiebel, James, Chang, Susan M., Cloughesy, Timothy F., Junck, Larry, Wen, Patrick, Lieberman, Frank, Conrad, Charles A., Gilbert, Mark R., Meyers, Christina A., Liu, Vivien, Mehta, Minesh P., Nicholas, M. Kelly, Prados, Michael
Publicado em 2004

Progression-free survival: An important end point in evaluating therapy for recurrent high-grade gliomas

Por Lamborn, Kathleen R., Alfred Yung, W. K., Chang, Susan M., Wen, Patrick Y., Cloughesy, Timothy F., DeAngelis, Lisa M., Robins, H. Ian, Lieberman, Frank S., Fine, Howard A., Fink, Karen L., Junck, Larry, Abrey, Lauren, Gilbert, Mark R., Mehta, Minesh, Kuhn, John G., Aldape, Kenneth D., Hibberts, Janelle, Peterson, Pamela M., Prados, Michael D.
Publicado em 2008

Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02

Por Wen, Patrick Y., Chang, Susan M., Lamborn, Kathleen R., Kuhn, John G., Norden, Andrew D., Cloughesy, Timothy F., Robins, H. Ian, Lieberman, Frank S., Gilbert, Mark R., Mehta, Minesh P., Drappatz, Jan, Groves, Morris D., Santagata, Sandro, Ligon, Azra H., Yung, W.K. Alfred, Wright, John J., Dancey, Janet, Aldape, Kenneth D., Prados, Michael D., Ligon, Keith L.
Publicado em 2014

Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03

Por Lee, Eudocia Q., Puduvalli, Vinay K., Reid, Joel M., Kuhn, John G., Lamborn, Kathleen R., Cloughesy, Timothy F., Chang, Susan M., Drappatz, Jan, Yung, W. K. Alfred, Gilbert, Mark R., Robins, H. Ian, Lieberman, Frank S., Lassman, Andrew B., McGovern, Renee M., Xu, Jihong, Desideri, Serena, Ye, Xiabu, Ames, Matthew M., Espinoza-Delgado, Igor, Prados, Michael D., Wen, Patrick Y.
Publicado em 2012

Toward precision medicine in glioblastoma: the promise and the challenges

Por Prados, Michael D., Byron, Sara A., Tran, Nhan L., Phillips, Joanna J., Molinaro, Annette M., Ligon, Keith L., Wen, Patrick Y., Kuhn, John G., Mellinghoff, Ingo K., de Groot, John F., Colman, Howard, Cloughesy, Timothy F., Chang, Susan M., Ryken, Timothy C., Tembe, Waibhav D., Kiefer, Jeffrey A., Berens, Michael E., Craig, David W., Carpten, John D., Trent, Jeffrey M.
Publicado no Neuro Oncol (2015)

EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Anti-Lipogenic Therapy

Por Guo, Deliang, Prins, Robert M., Dang, Julie, Kuga, Daisuke, Iwanami, Akio, Soto, Horacio, Lin, Kelly Y., Huang, Tiffany T., Akhavan, David, Hock, M. Benjamin, Kofman, Ava A., Bensinger, Steve J., Yong, William H., Vinters, Harry V., Horvath, Steve, Watson, Andrew D., Kuhn, John G., Robins, H. Ian, Mehta, Minesh P., Wen, Patrick Y., DeAngelis, Lisa M., Prados, Michael D., Mellinghoff, Ingo K., Cloughesy, Timothy F., Mischel, Paul S.
Publicado em 2009

Differential Sensitivity of Glioma- versus Lung Cancer-specific EGFR mutations to EGFR Kinase Inhibitors

Por Vivanco, Igor, Robins, H. Ian, Rohle, Daniel, Campos, Carl, Grommes, Christian, Nghiemphu, Phioanh Leia, Kubek, Sara, Oldrini, Barbara, Chheda, Milan G., Yannuzzi, Nicolas, Tao, Hui, Zhu, Shaojun, Iwanami, Akio, Kuga, Daisuke, Dang, Julie, Pedraza, Alicia, Brennan, Cameron W., Heguy, Adriana, Liau, Linda M., Lieberman, Frank, Yung, W.K. Alfred, Gilbert, Mark R., Reardon, David A., Drappatz, Jan, Wen, Patrick Y., Lamborn, Kathleen R., Chang, Susan M., Prados, Michael D., Fine, Howard A., Horvath, Steve, Wu, Nian, Lassman, Andrew B., DeAngelis, Lisa M., Yong, William H., Kuhn, John G., Mischel, Paul S., Mehta, Minesh P., Cloughesy, Timothy F., Mellinghoff, Ingo K.
Publicado em 2012