Predicting Success in Regulatory Approval From Phase I Results

Por Malik, Laeeq, Mejia, Alex, Parsons, Helen, Ehler, Benjamin, Mahalingam, Devalingam, Brenner, Andrew, Sarantopoulos, John, Weitman, Steven
Publicado no Cancer Chemother Pharmacol (2014)

Should we move beyond VEGF inhibition in metastatic colorectal cancer? Lessons from early phase clinical trials

Por Patel, Sukeshi R., Karnad, Anand B., Ketchum, Norma S., Pollock, Brad H., Sarantopoulos, John, Weitman, Steven, Mahalingam, Devalingam
Publicado em 2014

Early Phase Clinical Trials: Referral Barriers and Promoters among Physicians

Por Ramirez, Amelie G., Chalela, Patricia, Suarez, Lucina, Muñoz, Edgar, Pollock, Brad H., Weitman, Steven D., Gallion, Kipling J.
Publicado em 2012

Safety and pharmacodynamics of the PDE4 inhibitor roflumilast in advanced B cell malignancies

Por Kelly, Kevin, Mejia, Alex, Suhasini, Avvaru, Lin, An-Ping, Kuhn, John, Karnad, Anand B., Weitman, Steven, Aguiar, Ricardo C. T.
Publicado no Clin Cancer Res (2016)

Promoting Factors and Barriers to Participation in Early Phase Clinical Trials: Patients Perspectives

Por Chalela, Patricia, Suarez, Lucina, Muñoz, Edgar, Gallion, Kipling J., Pollock, Brad H., Weitman, Steven D., Karnad, Anand, Ramirez, Amelie G.
Publicado em 2014

Safety, tolerability, and preliminary activity of IMGN529, a CD37-targeted antibody-drug conjugate, in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: a dose-esca...

Por Stathis, Anastasios, Flinn, Ian W., Madan, Sumit, Maddocks, Kami, Freedman, Arnold, Weitman, Steven, Zucca, Emanuele, Munteanu, Mihaela C., Lia Palomba, M.
Publicado no Invest New Drugs (2018)

Phase 1 study evaluating the safety and pharmacokinetics of pralatrexate in relapsed/refractory advanced solid tumors and lymphoma patients with mild, moderate, and severe renal im...

Por Kelly, Kevin R., Gabrail, Nashat, Weitman, Steven, Sarantopoulos, John, Olszanski, Anthony J., Edenfield, William, Venitz, Jurgen, Reddy, Guru, Yang, Allen, Hasal, Steven J., Lockhart, A. Craig
Publicado no Cancer Chemother Pharmacol (2016)

Metformin for Reducing Racial/Ethnic Difference in Prostate Cancer Incidence for Men with Type 2 Diabetes

Por Wang, Chen-Pin, Lehman, Donna M., Lam, Yui-Wing F., Kuhn, John G., Mahalingam, Devalingam, Weitman, Steven, Lorenzo, Carlos, Downs, John R., Stuart, Elizabeth A, Hernandez, Javier, Thompson, Ian M., Ramirez, Amelie G.
Publicado no Cancer Prev Res (Phila) (2016)

Combined venetoclax and alvocidib in acute myeloid leukemia

Por Bogenberger, James, Whatcott, Clifford, Hansen, Nanna, Delman, Devora, Shi, Chang-Xin, Kim, Wontak, Haws, Hillary, Soh, Katherine, Lee, Ye Sol, Peterson, Peter, Siddiqui-Jain, Adam, Weitman, Steven, Stewart, Keith, Bearss, David, Mesa, Ruben, Warner, Steven, Tibes, Raoul
Publicado no Oncotarget (2017)

Single-cell Analysis of Circulating Tumor Cells Identifies Cumulative Expression Patterns of EMT-related Genes in Metastatic Prostate Cancer

Por Chen, Chun-Liang, Mahalingam, Devalingam, Osmulski, Pawel, Jadhav, Rohit R., Wang, Chiou-Miin, Leach, Robin J., Chang, Tien-Cheng, Weitman, Steven D., Kumar, Addanki Pratap, Sun, LuZhe, Gaczynska, Maria E., Thompson, Ian M., Huang, Tim Hui-Ming
Publicado no Prostate (2012)

Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/Vincristine in Relapsed/Refractory Aggressive B-cell Lymphoma

Por Kelly, Kevin R., Friedberg, Jonathan W., Park, Steven I., McDonagh, Kevin, Hayslip, John, Persky, Daniel, Ruan, Jia, Puvvada, Soham, Rosen, Peter, Padmanabhan Iyer, Swaminathan, Stefanovic, Alexandra, Bernstein, Steven H., Weitman, Steven, Karnad, Anand, Monohan, Gregory, VanderWalde, Ari, Mena, Raul, Schmelz, Monika, Spier, Catherine, Groshen, Susan, Venkatakrishnan, Karthik, Zhou, Xiaofei, Sheldon-Waniga, Emily, Leonard, E. Jane, Mahadevan, Daruka
Publicado no Clin Cancer Res (2018)

Single-cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer

Por Taverna, Josephine A., Hung, Chia-Nung, DeArmond, Daniel T., Chen, Meizhen, Lin, Chun-Lin, Osmulski, Pawel A., Gaczynska, Maria E., Wang, Chiou-Miin, Lucio, Nicholas D., Chou, Chih-Wei, Chen, Chun-Liang, Nazarullah, Alia, Lampkin, Shellye R., Qiu, Lianqun, Bearss, David J., Warner, Steven, Whatcott, Clifford J., Mouritsen, Lars, Wade, Mark, Weitman, Steven, Mesa, Ruben A., Kirma, Nameer B., Chao, Wei-Ting, Huang, Tim H.-M.
Publicado no Cancer Res (2020)