Clinical Management of Adverse Events Associated with Lorlatinib

द्वारा Bauer, Todd M., Felip, Enriqueta, Solomon, Benjamin J., Thurm, Holger, Peltz, Gerson, Chioda, Marc D., Shaw, Alice T.
में प्रकाशित Oncologist (2019)

A Phase Ib study of ruxolitinib + gemcitabine ± nab-paclitaxel in patients with advanced solid tumors

द्वारा Bauer, Todd M, Patel, Manish R, Forero-Torres, Andres, George, Thomas J, Assad, Albert, Du, Yining, Hurwitz, Herbert
में प्रकाशित Onco Targets Ther (2018)

Phase I study of the investigational oral mTORC1/2 inhibitor sapanisertib (TAK-228): tolerability and food effects of a milled formulation in patients with advanced solid tumours

द्वारा Moore, Kathleen N, Bauer, Todd M, Falchook, Gerald S, Chowdhury, Swapan, Patel, Chirag, Neuwirth, Rachel, Enke, Aaron, Zohren, Fabian, Patel, Manish R
में प्रकाशित ESMO Open (2018)

Pharmacokinetics of carfilzomib in patients with advanced malignancies and varying degrees of hepatic impairment: an open-label, single-arm, phase 1 study

द्वारा Brown, Jennifer, Plummer, Ruth, Bauer, Todd M., Anthony, Stephen, Sarantopoulos, John, De Vos, Filip, White, Mike, Schupp, Marco, Ou, Ying, Vaishampayan, Ulka
में प्रकाशित Exp Hematol Oncol (2017)

Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours

द्वारा Faessel, Hélène, Nemunaitis, John, Bauer, Todd M., Lockhart, A. Craig, Faller, Douglas V., Sedarati, Farhad, Zhou, Xiaofei, Venkatakrishnan, Karthik, Harvey, R. Donald
में प्रकाशित Br J Clin Pharmacol (2019)

Carbohydrate Antigen 19-9 Is a Prognostic and Predictive Biomarker in Patients With Advanced Pancreatic Cancer Who Receive Gemcitabine-Containing Chemotherapy: A Pooled Analysis of...

द्वारा Bauer, Todd M., El-Rayes, Bassel F., Li, Xiaobai, Hammad, Nazik, Philip, Philip A., Shields, Anthony F., Zalupski, Mark M., Bekaii-Saab, Tanios
में प्रकाशित Cancer (2012)

Brain Penetration of Lorlatinib: Cumulative Incidences of CNS and Non-CNS Progression with Lorlatinib in Patients with Previously Treated ALK-Positive Non-Small-Cell Lung Cancer

द्वारा Bauer, Todd M., Shaw, Alice T., Johnson, Melissa L., Navarro, Alejandro, Gainor, Justin F., Thurm, Holger, Pithavala, Yazdi K., Abbattista, Antonello, Peltz, Gerson, Felip, Enriqueta
में प्रकाशित Target Oncol (2020)

Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignancies

द्वारा Zhou, Xiaofei, Nemunaitis, John, Pant, Shubham, Bauer, Todd M., Patel, Manish, Sarantopoulos, John, Craig Lockhart, A., Goodman, Daniel, Huebner, Dirk, Mould, Diane R., Venkatakrishnan, Karthik
में प्रकाशित Invest New Drugs (2017)

Safety and Activity of Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha–Targeting Antibody–Drug Conjugate, in Platinum-Resistant Ovarian, Fallopian Tube, or Primary Per...

द्वारा Moore, Kathleen N., Martin, Lainie P., O’Malley, David M., Matulonis, Ursula A., Konner, Jason A., Perez, Raymond P., Bauer, Todd M., Ruiz-Soto, Rodrigo, Birrer, Michael J.
में प्रकाशित J Clin Oncol (2017)

Effects of rifampin, itraconazole and esomeprazole on the pharmacokinetics of alisertib, an investigational aurora a kinase inhibitor in patients with advanced malignancies

द्वारा Zhou, Xiaofei, Pant, Shubham, Nemunaitis, John, Craig Lockhart, A., Falchook, Gerald, Bauer, Todd M., Patel, Manish, Sarantopoulos, John, Bargfrede, Michael, Muehler, Andreas, Rangachari, Lakshmi, Zhang, Bin, Venkatakrishnan, Karthik
में प्रकाशित Invest New Drugs (2017)

Characterization and phase I study of CLR457, an orally bioavailable pan-class I PI3-kinase inhibitor

द्वारा Harding, James J., Bauer, Todd M., Tan, Daniel S. W., Bedard, Philippe L., Rodon, Jordi, Doi, Toshihiko, Schnell, Christian, Iyer, Varsha, Baffert, Fabienne, Radhakrishnan, Rajkumar, Fabre, Claire, Juric, Dejan
में प्रकाशित Invest New Drugs (2018)

Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study

द्वारा Piha-Paul, Sarina A., Taylor, Matthew H., Spitz, Daniel, Schwartzberg, Lee, Beck, J. Thaddeus, Bauer, Todd M., Meric-Bernstam, Funda, Purkayastha, Das, Karpiak, Linda, Szpakowski, Sebastian, Braiteh, Fadi
में प्रकाशित Oncotarget (2019)

Phase 1 cohort expansion study of LY3023414, a dual PI3K/mTOR inhibitor, in patients with advanced mesothelioma

द्वारा Zauderer, Marjorie G., Alley, Evan W., Bendell, Johanna, Capelletto, Enrica, Bauer, Todd M., Callies, Sophie, Szpurka, Anna M., Kang, Suhyun, Willard, Melinda D., Wacheck, Volker, Varghese, Anna M.
में प्रकाशित Invest New Drugs (2021)

Preliminary results from a Phase I/II study of epacadostat (incb024360) in combination with pembrolizumab in patients with selected advanced cancers

द्वारा Gangadhar, Tara C, Hamid, Omid, Smith, David C, Bauer, Todd M, Wasser, Jeffrey S, Luke, Jason J, Balmanoukian, Ani S, Kaufman, David R, Zhao, Yufan, Maleski, Janet, Leopold, Lance, Gajewski, Thomas F
में प्रकाशित J Immunother Cancer (2015)

Signature program: a platform of basket trials

द्वारा Slosberg, Eric D., Kang, Barinder P., Peguero, Julio, Taylor, Matthew, Bauer, Todd M., Berry, Donald A., Braiteh, Fadi, Spira, Alexander, Meric-Bernstam, Funda, Stein, Steven, Piha-Paul, Sarina A., Salvado, August
में प्रकाशित Oncotarget (2018)

Epacadostat Plus Pembrolizumab in Patients With Advanced Solid Tumors: Phase I Results From a Multicenter, Open-Label Phase I/II Trial (ECHO-202/KEYNOTE-037)

द्वारा Mitchell, Tara C., Hamid, Omid, Smith, David C., Bauer, Todd M., Wasser, Jeffrey S., Olszanski, Anthony J., Luke, Jason J., Balmanoukian, Ani S., Schmidt, Emmett V., Zhao, Yufan, Gong, Xiaohua, Maleski, Janet, Leopold, Lance, Gajewski, Thomas F.
में प्रकाशित J Clin Oncol (2018)

Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumo...

द्वारा Lockhart, A Craig, Bauer, Todd M., Aggarwal, Charu, Lee, Carrie B., Harvey, R Donald, Cohen, Roger B., Sedarati, Farhad, Nip, Tsz Keung, Faessel, Hélène, Dash, Ajeeta B., Dezube, Bruce J., Faller, Douglas V., Dowlati, Afshin
में प्रकाशित Invest New Drugs (2018)

Lorlatinib in ALK- or ROS1-rearranged non-small cell lung cancer: an international, multicenter, open-label phase 1 trial

द्वारा Shaw, Alice T., Felip, Enriqueta, Bauer, Todd M., Besse, Benjamin, Navarro, Alejandro, Postel-Vinay, Sophie, Gainor, Justin F., Johnson, Melissa, Dietrich, Jorg, James, Leonard P., Clancy, Jill S., Chen, Joseph, Martini, Jean-François, Abbattista, Antonello, Solomon, Benjamin J.
में प्रकाशित Lancet Oncol (2017)

Phase I Study of LY2606368, a Checkpoint Kinase 1 Inhibitor, in Patients With Advanced Cancer

द्वारा Hong, David, Infante, Jeffrey, Janku, Filip, Jones, Suzanne, Nguyen, Ly M., Burris, Howard, Naing, Aung, Bauer, Todd M., Piha-Paul, Sarina, Johnson, Faye M., Kurzrock, Razelle, Golden, Lisa, Hynes, Scott, Lin, Ji, Lin, Aimee Bence, Bendell, Johanna
में प्रकाशित J Clin Oncol (2016)

Phase 1 Dose-Escalation Study of Mirvetuximab Soravtansine (IMGN853), a Folate Receptor α-Targeting Antibody-Drug Conjugate, in Patients With Solid Tumors

द्वारा Moore, Kathleen N., Borghaei, Hossein, O’Malley, David M., Jeong, Woondong, Seward, Shelly M., Bauer, Todd M., Perez, Raymond P., Matulonis, Ursula A., Running, Kelli L., Zhang, Xiaoyan, Ponte, Jose F., Ruiz-Soto, Rodrigo, Birrer, Michael J.
में प्रकाशित Cancer (2017)