The case for regulating indispensable amino acid metabolism: the branched-chain α-keto acid dehydrogenase kinase-knockout mouse

Por Hutson, Susan M.
Publicado em 2006

siRNA silencing of calumenin enhances functional factor IX production

Por Wajih, Nadeem, Hutson, Susan M., Wallin, Reidar
Publicado em 2006

Expression of mitochondrial branched-chain aminotransferase and α-keto-acid dehydrogenase in rat brain: implications for neurotransmitter metabolism

Por Cole, Jeffrey T., Sweatt, Andrew J., Hutson, Susan M.
Publicado em 2012

Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond(1)(2)(3)

Por Ananieva, Elitsa A, Powell, Jonathan D, Hutson, Susan M
Publicado no Adv Nutr (2016)

Liver BCATm transgenic mouse model reveals the important role of the liver in maintaining BCAA homeostasis

Por Ananieva, Elitsa A., Van Horn, Cynthia G., Jones, Meghan R., Hutson, Susan M.
Publicado no J Nutr Biochem (2016)

Cytosolic Branched Chain Aminotransferase (BCATc) Regulates mTORC1 Signaling and Glycolytic Metabolism in CD4(+) T Cells

Por Ananieva, Elitsa A., Patel, Chirag H., Drake, Charles H., Powell, Jonathan D., Hutson, Susan M.
Publicado em 2014

Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched chain amino acid (BCAA) metabolism

Por She, Pengxiang, Van Horn, Cynthia, Reid, Tanya, Hutson, Susan M., Cooney, Robert N., Lynch, Christopher J.
Publicado em 2007

Branched-chain Amino Acid Metabolon: INTERACTION OF GLUTAMATE DEHYDROGENASE WITH THE MITOCHONDRIAL BRANCHED-CHAIN AMINOTRANSFERASE (BCATm)

Por Islam, Mohammad Mainul, Nautiyal, Manisha, Wynn, R. Max, Mobley, James A., Chuang, David T., Hutson, Susan M.
Publicado em 2010

Lactating Porcine Mammary Tissue Catabolizes Branched-Chain Amino Acids for Glutamine and Aspartate Synthesis

Por Li, Peng, Knabe, Darrell A., Kim, Sung Woo, Lynch, Christopher J., Hutson, Susan M., Wu, Guoyao
Publicado em 2009

Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia

Por Ashby, Emma L., Kierzkowska, Marta, Hull, Jonathon, Kehoe, Patrick G., Hutson, Susan M., Conway, Myra E.
Publicado no Neurochem Res (2016)

Functional impact of high protein intake on healthy elderly people

Por Walrand, Stephane, Short, Kevin R., Bigelow, Maureen L., Sweatt, Andrew J., Hutson, Susan M., Nair, K. Sreekumaran
Publicado em 2008

Impaired branched-chain amino acid metabolism alters feeding behavior and increases orexigenic neuropeptide expression in the hypothalamus

Por Purpera, Megan N., Shen, Li, Taghavi, Marzieh, Münzberg, Heike, Martin, Roy J., Hutson, Susan M., Morrison, Christopher D.
Publicado em 2011

Mex3c Mutation Reduces Adiposity and Increases Energy Expenditure

Por Jiao, Yan, George, Sunil K., Zhao, Qingguo, Hulver, Matthew W., Hutson, Susan M., Bishop, Colin E., Lu, Baisong
Publicado em 2012

Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle

Por She, Pengxiang, Reid, Tanya M., Bronson, Sarah K., Vary, Thomas C., Hajnal, Andras, Lynch, Christopher J, Hutson, Susan M.
Publicado em 2007

Leucine and α-Ketoisocaproic Acid, but Not Norleucine, Stimulate Skeletal Muscle Protein Synthesis in Neonatal Pigs

Por Escobar, Jeffery, Frank, Jason W., Suryawan, Agus, Nguyen, Hanh V., Van Horn, Cynthia G., Hutson, Susan M., Davis, Teresa A.
Publicado em 2010

Leucine acts in the brain to suppress food intake but does not function as a physiological signal of low dietary protein

Por Laeger, Thomas, Reed, Scott D., Henagan, Tara M., Fernandez, Denise H., Taghavi, Marzieh, Addington, Adele, Münzberg, Heike, Martin, Roy J., Hutson, Susan M., Morrison, Christopher D.
Publicado em 2014

FGF21 is an endocrine signal of protein restriction

Por Laeger, Thomas, Henagan, Tara M., Albarado, Diana C., Redman, Leanne M., Bray, George A., Noland, Robert C., Münzberg, Heike, Hutson, Susan M., Gettys, Thomas W., Schwartz, Michael W., Morrison, Christopher D.
Publicado em 2014

Phenylbutyrate therapy for maple syrup urine disease

Por Brunetti-Pierri, Nicola, Lanpher, Brendan, Erez, Ayelet, Ananieva, Elitsa A., Islam, Mohammad, Marini, Juan C., Sun, Qin, Yu, Chunli, Hegde, Madhuri, Li, Jun, Wynn, R. Max, Chuang, David T., Hutson, Susan, Lee, Brendan
Publicado em 2011

Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase

Por Tso, Shih-Chia, Qi, Xiangbing, Gui, Wen-Jun, Chuang, Jacinta L., Morlock, Lorraine K., Wallace, Amy L., Ahmed, Kamran, Laxman, Sunil, Campeau, Philippe M., Lee, Brendan H., Hutson, Susan M., Tu, Benjamin P., Williams, Noelle S., Tambar, Uttam K., Wynn, R. Max, Chuang, David T.
Publicado em 2013

Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase

Por Tso, Shih-Chia, Gui, Wen-Jun, Wu, Cheng-Yang, Chuang, Jacinta L., Qi, Xiangbing, Skvorak, Kristen J., Dorko, Kenneth, Wallace, Amy L., Morlock, Lorraine K., Lee, Brendan H., Hutson, Susan M., Strom, Stephen C., Williams, Noelle S., Tambar, Uttam K., Wynn, R. Max, Chuang, David T.
Publicado em 2014