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siRNA silencing of calumenin enhances functional factor IX production
To improve production of functional fully γ-carboxylated recombinant human clotting factor IX (r-hFIX), cell lines stably overexpressing r-hFIX have been engineered to also overexpress proteins of the γ-carboxylation system. Here we demonstrate that siRNA silencing of calumenin, an inhibitor of the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Hematology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895465/ https://ncbi.nlm.nih.gov/pubmed/16902154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-004671 |
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