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Dextran functionalization enhances nanoparticle-mediated siRNA delivery and silencing

Understanding the endocytosis and intracellular trafficking of short interfering RNA (siRNA) delivery vehicle complexes remains a critical bottleneck in designing siRNA delivery vehicles for highly active RNA interference (RNAi)-based therapeutics. In this study, we show that dextran functionalizati...

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Detalhes bibliográficos
Publicado no:Technology (Singap World Sci)
Main Authors: Vocelle, Daniel, Chesniak, Olivia M., Malefyt, Amanda P., Comiskey, Georgina, Adu-Berchie, Kwasi, Smith, Milton R., Chan, Christina, Walton, S. Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072529/
https://ncbi.nlm.nih.gov/pubmed/27774502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S2339547816400100
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