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Endocytosis Controls siRNA Efficiency: Implications for siRNA Delivery Vehicle Design and Cell-Specific Targeting

While small interfering RNAs (siRNAs) are commonly used for laboratory studies, development of siRNA therapeutics has been slower than expected, due, in part, to a still limited understanding of the endocytosis and intracellular trafficking of siRNA-containing complexes. With the recent characteriza...

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Detalhes bibliográficos
Publicado no:Nucleic Acid Ther
Main Authors: Vocelle, Daniel, Chan, Christina, Walton, S. Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987736/
https://ncbi.nlm.nih.gov/pubmed/31718426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2019.0804
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