Modulating Polymer-siRNA Binding Does Not Promote Polyplex-Mediated Silencing

The development of delivery vehicles for small interfering RNAs (siRNAs) remains a bottleneck to widespread clinical use. Cationic polymers represent an important class of potential delivery vehicles. In this study, we used alkyne-azide click chemistry to synthesize a variety of cationic poly(propar...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acid Ther
Auteurs principaux: Splichal, R. Chauncey, Gredell, Joseph A., Vogel, Erin B., Malefyt, Amanda, Comiskey, Georgina, Smith, Milton R., Chan, Christina, Walton, S. Patrick
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc., publishers 2021
Sujets:
Original Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215420/
https://ncbi.nlm.nih.gov/pubmed/32749923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2020.0857
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires