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Impact of target mRNA structure on siRNA silencing efficiency: a large-scale study
The selection of active siRNAs is generally based on identifying siRNAs with certain sequence and structural properties. However, the efficiency of RNA interference has also been shown to depend on the structure of the target mRNA, primarily through studies using exogenous transcripts with well-defi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658823/ https://ncbi.nlm.nih.gov/pubmed/18306428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.21798 |
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