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Improved asymmetry prediction for siRNAs
In the development of RNA interference (RNAi) therapeutics, merely selecting short, interfering RNA (siRNA) sequences that are complementary to the messenger RNA (mRNA) target does not guarantee target silencing. Current algorithms for selecting siRNAs rely on many parameters, one of which is asymme...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3924726/ https://ncbi.nlm.nih.gov/pubmed/24393396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12599 |
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