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Designing Highly Active siRNAs for Therapeutic Applications

The discovery of RNA interference (RNAi) generated considerable interest in developing short interfering RNAs (siRNAs) for understanding basic biology and as the active agents in a new variety of therapeutics. Early studies showed that selecting an active siRNA was not as straightforward as simply p...

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Библиографические подробности
Главные авторы: Walton, S. Patrick, Wu, Ming, Gredell, Joseph A., Chan, Christina
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052974/
https://ncbi.nlm.nih.gov/pubmed/21078115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07903.x
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