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Designing Highly Active siRNAs for Therapeutic Applications

The discovery of RNA interference (RNAi) generated considerable interest in developing short interfering RNAs (siRNAs) for understanding basic biology and as the active agents in a new variety of therapeutics. Early studies showed that selecting an active siRNA was not as straightforward as simply p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Walton, S. Patrick, Wu, Ming, Gredell, Joseph A., Chan, Christina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052974/
https://ncbi.nlm.nih.gov/pubmed/21078115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07903.x
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