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Designing Highly Active siRNAs for Therapeutic Applications
The discovery of RNA interference (RNAi) generated considerable interest in developing short interfering RNAs (siRNAs) for understanding basic biology and as the active agents in a new variety of therapeutics. Early studies showed that selecting an active siRNA was not as straightforward as simply p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052974/ https://ncbi.nlm.nih.gov/pubmed/21078115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07903.x |
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