FGF21 is an endocrine signal of protein restriction

Enhanced fibroblast growth factor 21 (FGF21) production and circulation has been linked to the metabolic adaptation to starvation. Here, we demonstrated that hepatic FGF21 expression is induced by dietary protein restriction, but not energy restriction. Circulating FGF21 was increased 10-fold in mic...

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Bibliografiske detaljer
Main Authors: Laeger, Thomas, Henagan, Tara M., Albarado, Diana C., Redman, Leanne M., Bray, George A., Noland, Robert C., Münzberg, Heike, Hutson, Susan M., Gettys, Thomas W., Schwartz, Michael W., Morrison, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153701/
https://ncbi.nlm.nih.gov/pubmed/25133427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74915
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