FGF21 is an endocrine signal of protein restriction

Enhanced fibroblast growth factor 21 (FGF21) production and circulation has been linked to the metabolic adaptation to starvation. Here, we demonstrated that hepatic FGF21 expression is induced by dietary protein restriction, but not energy restriction. Circulating FGF21 was increased 10-fold in mic...

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Detalhes bibliográficos
Main Authors: Laeger, Thomas, Henagan, Tara M., Albarado, Diana C., Redman, Leanne M., Bray, George A., Noland, Robert C., Münzberg, Heike, Hutson, Susan M., Gettys, Thomas W., Schwartz, Michael W., Morrison, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153701/
https://ncbi.nlm.nih.gov/pubmed/25133427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74915
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