Overexpression of the Rv0805 phosphodiesterase elicits a cAMP-independent transcriptional response()

Por Matange, Nishad, Hunt, Debbie M., Buxton, Roger S., Visweswariah, Sandhya S.
Publicado em 2013

Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2

Por Stapleton, Melanie R., Smith, Laura J., Hunt, Debbie M., Buxton, Roger S., Green, Jeffrey
Publicado em 2012

Long range transcriptional control of virulence critical genes in Mycobacterium tuberculosis by nucleoid-associated proteins?

Por Buxton, Roger S., Green, Jeffrey, Hunt, Debbie M., Kahramanoglou, Christina, Stapleton, Melanie R., Sweeney, Nathan P.
Publicado em 2012

Genomic mapping of cAMP receptor protein (CRP(Mt)) in Mycobacterium tuberculosis: relation to transcriptional start sites and the role of CRP(Mt) as a transcription factor

Por Kahramanoglou, Christina, Cortes, Teresa, Matange, Nishad, Hunt, Debbie M., Visweswariah, Sandhya S., Young, Douglas B., Buxton, Roger S.
Publicado em 2014

Mycobacterium tuberculosis cAMP Receptor Protein (Rv3676) Differs from the Escherichia coli Paradigm in Its cAMP Binding and DNA Binding Properties and Transcription Activation Pro...

Por Stapleton, Melanie, Haq, Ihtshamul, Hunt, Debbie M., Arnvig, Kristine B., Artymiuk, Peter J., Buxton, Roger S., Green, Jeffrey
Publicado em 2010

Discovery of a glycerol 3-phosphate phosphatase reveals glycerophospholipid polar head recycling in Mycobacterium tuberculosis

Por Larrouy-Maumus, Gérald, Biswas, Tapan, Hunt, Debbie M., Kelly, Geoff, Tsodikov, Oleg V., de Carvalho, Luiz Pedro Sório
Publicado em 2013

Cyclic-AMP and bacterial cyclic-AMP receptor proteins revisited: adaptation for different ecological niches()

Por Green, Jeffrey, Stapleton, Melanie R, Smith, Laura J, Artymiuk, Peter J, Kahramanoglou, Christina, Hunt, Debbie M, Buxton, Roger S
Publicado em 2014

Genome structure in the vole bacillus, Mycobacterium microti, a member of the Mycobacterium tuberculosis complex with a low virulence for humans

Por Frota, Cristiane C., Hunt, Debbie M., Buxton, Roger S., Rickman, Lisa, Hinds, Jason, Kremer, Kristin, van Soolingen, Dick, Colston, M. Joseph
Publicado em 2004

A two-component signal transduction system with a PAS domain-containing sensor is required for virulence of Mycobacterium tuberculosis in mice

Por Rickman, Lisa, Saldanha, José W., Hunt, Debbie M., Hoar, Dominic N., Colston, M. Joseph, Millar, Jonathan B.A., Buxton, Roger S.
Publicado em 2004

Single Nucleotide Polymorphisms That Cause Structural Changes in the Cyclic AMP Receptor Protein Transcriptional Regulator of the Tuberculosis Vaccine Strain Mycobacterium bovis BC...

Por Hunt, Debbie M., Saldanha, José W., Brennan, John F., Benjamin, Pearline, Strom, Molly, Cole, Jeffrey A., Spreadbury, Claire L., Buxton, Roger S.
Publicado em 2008

An ABC Transporter Containing a Forkhead-Associated Domain Interacts with a Serine-Threonine Protein Kinase and Is Required for Growth of Mycobacterium tuberculosis in Mice

Por Curry, Juliet M., Whalan, Rachael, Hunt, Debbie M., Gohil, Kalpesh, Strom, Molly, Rickman, Lisa, Colston, M. Joseph, Smerdon, Stephen J., Buxton, Roger S.
Publicado em 2005

A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene...

Por Rickman, Lisa, Scott, Colin, Hunt, Debbie M., Hutchinson, Thomas, Menéndez, M. Carmen, Whalan, Rachael, Hinds, Jason, Colston, M. Joseph, Green, Jeffrey, Buxton, Roger S.
Publicado em 2005

Structure of a Wbl protein and implications for NO sensing by M. tuberculosis

Por Kudhair, Bassam K., Hounslow, Andrea M., Rolfe, Matthew D., Crack, Jason C., Hunt, Debbie M., Buxton, Roger S., Smith, Laura J., Le Brun, Nick E., Williamson, Michael P., Green, Jeffrey
Publicado no Nat Commun (2017)

Long-Range Transcriptional Control of an Operon Necessary for Virulence-Critical ESX-1 Secretion in Mycobacterium tuberculosis

Por Hunt, Debbie M., Sweeney, Nathan P., Mori, Luisa, Whalan, Rachael H., Comas, Iñaki, Norman, Laura, Cortes, Teresa, Arnvig, Kristine B., Davis, Elaine O., Stapleton, Melanie R., Green, Jeffrey, Buxton, Roger S.
Publicado em 2012

Cell-Envelope Remodeling as a Determinant of Phenotypic Antibacterial Tolerance in Mycobacterium tuberculosis

Por Larrouy-Maumus, Gérald, Marino, Leonardo B., Madduri, Ashoka V. R., Ragan, T. J., Hunt, Debbie M., Bassano, Lucrezia, Gutierrez, Maximiliano G., Moody, D. Branch, Pavan, Fernando R., de Carvalho, Luiz Pedro S.
Publicado no ACS Infect Dis (2016)

Mycobacterium tuberculosis WhiB1 is an essential DNA-binding protein with a nitric oxide sensitive iron-sulphur cluster

Por Smith, Laura J., Stapleton, Melanie R., Fullstone, Gavin J. M., Crack, Jason C., Thomson, Andrew J., Le Brun, Nick E., Hunt, Debbie M., Harvey, Evelyn, Adinolfi, Salvatore, Buxton, Roger S., Green, Jeffrey
Publicado em 2010

Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence

Por Smith, Laura J., Bochkareva, Aleksandra, Rolfe, Matthew D., Hunt, Debbie M., Kahramanoglou, Christina, Braun, Yvonne, Rodgers, Angela, Blockley, Alix, Coade, Stephen, Lougheed, Kathryn E.A., Hafneh, Nor Azian, Glenn, Sarah M., Crack, Jason C., Le Brun, Nick E., Saldanha, José W., Makarov, Vadim, Nobeli, Irene, Arnvig, Kristine, Mukamolova, Galina V., Buxton, Roger S., Green, Jeffrey
Publicado no Nucleic Acids Res (2017)

Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity

Por dos Santos Fernandes, Guilherme Felipe, de Souza, Paula Carolina, Moreno-Viguri, Elsa, Santivañez-Veliz, Mery, Paucar, Rocio, Pérez-Silanes, Silvia, Chegaev, Konstantin, Guglielmo, Stefano, Lazzarato, Loretta, Fruttero, Roberta, Man Chin, Chung, da Silva, Patricia Bento, Chorilli, Marlus, Solcia, Mariana Cristina, Ribeiro, Camila Maríngolo, Silva, Caio Sander Paiva, Marino, Leonardo Biancolino, Bosquesi, Priscila Longhin, Hunt, Debbie M., de Carvalho, Luiz Pedro S., de Souza Costa, Carlos Alberto, Cho, Sang Hyun, Wang, Yuehong, Franzblau, Scott Gary, Pavan, Fernando Rogério, dos Santos, Jean Leandro
Publicado no J Med Chem (2017)