A Drosophila model for primary coenzyme Q deficiency and dietary rescue in the developing nervous system

por Grant, Jennifer, Saldanha, José W., Gould, Alex P.
Publicado 2010

A complete, multi-level conformational clustering of antibody complementarity-determining regions

por Nikoloudis, Dimitris, Pitts, Jim E., Saldanha, José W.
Publicado 2014

Disjoint combinations profiling (DCP): a new method for the prediction of antibody CDR conformation from sequence

por Nikoloudis, Dimitris, Pitts, Jim E., Saldanha, José W.
Publicado 2014

Characterization of Wise Protein and Its Molecular Mechanism to Interact with both Wnt and BMP Signals

por Lintern, Katherine B., Guidato, Sonia, Rowe, Alison, Saldanha, José W., Itasaki, Nobue
Publicado 2009

Helix 8 of the M(1) Muscarinic Acetylcholine Receptor: Scanning Mutagenesis Delineates a G Protein Recognition Site

por Kaye, Robert G., Saldanha, José W., Lu, Zhi-Liang, Hulme, Edward C.
Publicado 2011

MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer

por Qi, Wenqing, Cooke, Larry S, Stejskal, Amy, Riley, Christopher, Croce, Kimiko Della, Saldanha, Jose W, Bearss, David, Mahadevan, Daruka
Publicado 2009

The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly

por Smith, Stuart J., Towers, Norma, Saldanha, José W., Shang, Catherine A., Mahmood, S. Radma, Taylor, William R., Mohun, Timothy J.
Publicado en Dev Biol (2016)

A two-component signal transduction system with a PAS domain-containing sensor is required for virulence of Mycobacterium tuberculosis in mice

por Rickman, Lisa, Saldanha, José W., Hunt, Debbie M., Hoar, Dominic N., Colston, M. Joseph, Millar, Jonathan B.A., Buxton, Roger S.
Publicado 2004

Single Nucleotide Polymorphisms That Cause Structural Changes in the Cyclic AMP Receptor Protein Transcriptional Regulator of the Tuberculosis Vaccine Strain Mycobacterium bovis BC...

por Hunt, Debbie M., Saldanha, José W., Brennan, John F., Benjamin, Pearline, Strom, Molly, Cole, Jeffrey A., Spreadbury, Claire L., Buxton, Roger S.
Publicado 2008

Crystal structure reveals conservation of amyloid-β conformation recognized by 3D6 following humanization to bapineuzumab

por Feinberg, Hadar, Saldanha, José W, Diep, Linnea, Goel, Amita, Widom, Angela, Veldman, Geertruida M, Weis, William I, Schenk, Dale, Basi, Guriqbal S
Publicado 2014

FAN1 Activity on Asymmetric Repair Intermediates Is Mediated by an Atypical Monomeric Virus-type Replication-Repair Nuclease Domain

por Pennell, Simon, Déclais, Anne-Cécile, Li, Jiejin, Haire, Lesley F., Berg, Wioletta, Saldanha, José W., Taylor, Ian A., Rouse, John, Lilley, David M.J., Smerdon, Stephen J.
Publicado 2014

Novel application of luciferase assay for the in vitro functional assessment of KAL1 variants in three females with septo-optic dysplasia (SOD)

por McCabe, Mark J., Hu, Youli, Gregory, Louise C., Gaston-Massuet, Carles, Alatzoglou, Kyriaki S., Saldanha, José W., Gualtieri, Angelica, Thankamony, Ajay, Hughes, Ieuan, Townshend, Sharron, Martinez-Barbera, Juan-Pedro, Bouloux, Pierre-Marc, Dattani, Mehul T.
Publicado en Mol Cell Endocrinol (2015)

TRNT1 deficiency: clinical, biochemical and molecular genetic features

por Wedatilake, Yehani, Niazi, Rojeen, Fassone, Elisa, Powell, Christopher A., Pearce, Sarah, Plagnol, Vincent, Saldanha, José W., Kleta, Robert, Chong, W Kling, Footitt, Emma, Mills, Philippa B., Taanman, Jan-Willem, Minczuk, Michal, Clayton, Peter T., Rahman, Shamima
Publicado en Orphanet J Rare Dis (2016)

Design and Activity of a Murine and Humanized anti-CEACAM6 scFv in the Treatment of Pancreatic Cancer

por Riley, Christopher J., Engelhardt, Kevin P., Saldanha, Jose W., Qi, Wenqing, Cooke, Laurence S., Zhu, Yingting, Narayan, Satya T., Shakalya, Kishore, Croce, Kimiko Della, Georgiev, Ivan G., Nagle, Raymond B., Garewal, Harinder, Von Hoff, Daniel D., Mahadevan, Daruka
Publicado 2009

Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K

por Lisgarten, David R., Palmer, Rex A., Lobley, Carina M. C., Naylor, Claire E., Chowdhry, Babur Z., Al-Kurdi, Zakieh I., Badwan, Adnan A., Howlin, Brendan J., Gibbons, Nicholas C. J., Saldanha, José W., Lisgarten, John N., Basak, Ajit K.
Publicado en Chem Cent J (2017)

Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence

por Smith, Laura J., Bochkareva, Aleksandra, Rolfe, Matthew D., Hunt, Debbie M., Kahramanoglou, Christina, Braun, Yvonne, Rodgers, Angela, Blockley, Alix, Coade, Stephen, Lougheed, Kathryn E.A., Hafneh, Nor Azian, Glenn, Sarah M., Crack, Jason C., Le Brun, Nick E., Saldanha, José W., Makarov, Vadim, Nobeli, Irene, Arnvig, Kristine, Mukamolova, Galina V., Buxton, Roger S., Green, Jeffrey
Publicado en Nucleic Acids Res (2017)