A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor

Deletion of gene Rv3676 in Mycobacterium tuberculosis coding for a transcription factor belonging to the cAMP receptor protein (CRP) family caused growth defects in laboratory medium, in bone marrow-derived macrophages and in a mouse model of tuberculosis. Transcript profiling of M. tuberculosis gro...

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Detalhes bibliográficos
Main Authors: Rickman, Lisa, Scott, Colin, Hunt, Debbie M., Hutchinson, Thomas, Menéndez, M. Carmen, Whalan, Rachael, Hinds, Jason, Colston, M. Joseph, Green, Jeffrey, Buxton, Roger S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964915/
https://ncbi.nlm.nih.gov/pubmed/15882420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2005.04609.x
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