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Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2

A central feature of TB pathogenesis is the formation of Mycobacterium tuberculosis latent infections that can persist for decades. Nitric oxide produced by infected lung macrophages promotes expression of genes associated with dormancy, and impaired nitric oxide production can lead to reactivation...

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Main Authors: Stapleton, Melanie R., Smith, Laura J., Hunt, Debbie M., Buxton, Roger S., Green, Jeffrey
格式: Artigo
語言:Inglês
出版: Churchill Livingstone 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430963/
https://ncbi.nlm.nih.gov/pubmed/22464736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2012.03.001
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