Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2

A central feature of TB pathogenesis is the formation of Mycobacterium tuberculosis latent infections that can persist for decades. Nitric oxide produced by infected lung macrophages promotes expression of genes associated with dormancy, and impaired nitric oxide production can lead to reactivation...

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Detalles Bibliográficos
Autores principales: Stapleton, Melanie R., Smith, Laura J., Hunt, Debbie M., Buxton, Roger S., Green, Jeffrey
Formato: Artigo
Lenguaje:Inglês
Publicado: Churchill Livingstone 2012
Materias:
Molecular Aspects
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430963/
https://ncbi.nlm.nih.gov/pubmed/22464736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2012.03.001
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