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Structural and Functional Conservation of Mycobacterium tuberculosis GroEL Paralogs Suggests that GroEL1 is a Chaperonin

GroEL is a group I chaperonin that facilitates protein folding and prevents protein aggregation in the bacterial cytosol. Mycobacteria are unusual in encoding two or more copies of GroEL in their genome. While GroEL2 is essential for viability and likely functions as the general housekeeping chapero...

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Bibliographic Details
Main Authors: Sielaff, Bernhard, Lee, Ki Seog, Tsai, Francis T.F.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017675/
https://ncbi.nlm.nih.gov/pubmed/21094166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.021
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