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Structural and Functional Conservation of Mycobacterium tuberculosis GroEL Paralogs Suggests that GroEL1 is a Chaperonin

GroEL is a group I chaperonin that facilitates protein folding and prevents protein aggregation in the bacterial cytosol. Mycobacteria are unusual in encoding two or more copies of GroEL in their genome. While GroEL2 is essential for viability and likely functions as the general housekeeping chapero...

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Hlavní autoři: Sielaff, Bernhard, Lee, Ki Seog, Tsai, Francis T.F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017675/
https://ncbi.nlm.nih.gov/pubmed/21094166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.021
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