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Structural and Functional Conservation of Mycobacterium tuberculosis GroEL Paralogs Suggests that GroEL1 is a Chaperonin

GroEL is a group I chaperonin that facilitates protein folding and prevents protein aggregation in the bacterial cytosol. Mycobacteria are unusual in encoding two or more copies of GroEL in their genome. While GroEL2 is essential for viability and likely functions as the general housekeeping chapero...

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Detalhes bibliográficos
Main Authors: Sielaff, Bernhard, Lee, Ki Seog, Tsai, Francis T.F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017675/
https://ncbi.nlm.nih.gov/pubmed/21094166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.021
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