Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2

A central feature of TB pathogenesis is the formation of Mycobacterium tuberculosis latent infections that can persist for decades. Nitric oxide produced by infected lung macrophages promotes expression of genes associated with dormancy, and impaired nitric oxide production can lead to reactivation...

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Autors principals: Stapleton, Melanie R., Smith, Laura J., Hunt, Debbie M., Buxton, Roger S., Green, Jeffrey
Format: Artigo
Idioma:Inglês
Publicat: Churchill Livingstone 2012
Matèries:
Molecular Aspects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430963/
https://ncbi.nlm.nih.gov/pubmed/22464736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2012.03.001
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