Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoproteinmediated drug-drug interactions with dabigatran etexilate

Por Zhao, Yuansheng, Hu, Zhe-Yi
Publicado em 2014

A physiologically based pharmacokinetic model of alvespimycin in mice and extrapolation to rats and humans

Por Hu, Zhe-Yi, Lu, Jingtao, Zhao, Yuansheng
Publicado no Br J Pharmacol (2014)

In Vivo Information-Guided Prediction Approach for Assessing the Risks of Drug-Drug Interactions Associated with Circulating Inhibitory Metabolites

Por Hu, Zhe-Yi, Parker, Robert B., Laizure, S. Casey
Publicado em 2012

Effects of alcohol on human carboxylesterase drug metabolism

Por Parker, Robert B., Hu, Zhe-Yi, Meibohm, Bernd, Laizure, S. Casey
Publicado no Clin Pharmacokinet (2015)

Measurement of caffeine and its three primary metabolites in human plasma by HPLC-ESI-MS/MS and clinical application

Por Chen, Feng, Hu, Zhe-Yi, Parker, Robert B., Laizure, S. Casey
Publicado no Biomed Chromatogr (2017)

Conventional liquid chromatography/triple quadrupole mass spectrometer-based metabolite identification and semi-quantitative estimation approach in the investigation of dabigatran...

Por Hu, Zhe-Yi, Parker, Robert B., Herring, Vanessa L., Laizure, S. Casey
Publicado em 2012

Identification of Carboxylesterase-Dependent Dabigatran Etexilate Hydrolysis

Por Laizure, S. Casey, Parker, Robert B., Herring, Vanessa L., Hu, Zhe-Yi
Publicado em 2014

Evaluation of CYP3A activity in humans using three different parameters based on endogenous cortisol metabolism

Por Luo, Xi, Li, Xiao-min, Hu, Zhe-yi, Cheng, Ze-neng
Publicado em 2009

Identification of alcohol-dependent clopidogrel metabolites using conventional liquid chromatography/triple quadrupole mass spectrometry

Por Hu, Zhe-Yi, Laizure, S. Casey, Herring, Vanessa L., Parker, Robert B.
Publicado em 2014

Simple and sensitive assay for quantification of oseltamivir and its active metabolite oseltamivir carboxylate in human plasma using high-performance liquid chromatography coupled...

Por Hu, Zhe-Yi, Laizure, S. Casey, Meibohm, Bernd, Herring, Vanessa L., Parker, Robert B.
Publicado em 2012

Comparison of caffeine disposition following administration by oral solution (energy drink) and inspired powder (AeroShot) in human subjects

Por Laizure, S. Casey, Meibohm, Bernd, Nelson, Kembral, Chen, Feng, Hu, Zhe‐Yi, Parker, Robert B.
Publicado no Br J Clin Pharmacol (2017)

Nonvolatile salt-free stabilizer for the quantification of polar imipenem and cilastatin in human plasma using hydrophilic interaction chromatography/quadrupole mass spectrometry w...

Por Hu, Zhe-Yi, Boucher, Bradley A., Laizure, S. Casey, Herring, Vanessa L., Parker, Robert B., Hickerson, William L.
Publicado em 2013

Pharmacokinetic evaluation of the anticancer prodrug simmitecan in different experimental animals

Por Hu, Zhe-yi, Li, Xiu-xue, Du, Fei-fei, Yang, Jun-ling, Niu, Wei, Xu, Fang, Wang, Feng-qing, Li, Chuan, Sun, Yan
Publicado em 2013

Evaluation of the Highly Variable Agomelatine Pharmacokinetics in Chinese Healthy Subjects to Support Bioequivalence Study

Por Pei, Qi, Wang, Yan, Hu, Zhe-Yi, Liu, Shi-Kun, Tan, Hong-Yi, Guo, Cheng-Xian, Zhang, Ran-Ran, Xiang, Yu-Xia, Huang, Jie, Huang, Lu, Yuan, Hong, Yang, Guo-Ping
Publicado em 2014