Evaluation of the Highly Variable Agomelatine Pharmacokinetics in Chinese Healthy Subjects to Support Bioequivalence Study

OBJECTIVES: We aim to obtain the intra-subject coefficient of variability of a highly variable antidepressant agomelatine in humans, and propose an adjusted bioequivalence assessment strategy. METHODS: A single-dose, randomized crossover design was conducted in four periods (reference administered t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pei, Qi, Wang, Yan, Hu, Zhe-Yi, Liu, Shi-Kun, Tan, Hong-Yi, Guo, Cheng-Xian, Zhang, Ran-Ran, Xiang, Yu-Xia, Huang, Jie, Huang, Lu, Yuan, Hong, Yang, Guo-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203722/
https://ncbi.nlm.nih.gov/pubmed/25330096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109300
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados