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Bioequivalence and Pharmacokinetic Profiles of Generic and Branded Obeticholic Acid in Healthy Chinese Subjects Under Fasting and Fed Conditions

OBJECTIVES: This study was conducted to evaluate the bioequivalence (BE) of a generic form of obeticholic acid (OCA) and Ocaliva(TM) under fasting and fed conditions and to determine the effects of food on the pharmacokinetic (PK) profiles of OCA in healthy Chinese subjects. METHODS: A randomized, s...

詳細記述

保存先:
書誌詳細
出版年:Drug Des Devel Ther
主要な著者: Wang, Meng-Na, Yu, Hai-Tao, Li, Ya-Qian, Zeng, Yun, Yang, Shuang, Yang, Guo-Ping, Pei, Qi, Huang, Jie
フォーマット: Artigo
言語:Inglês
出版事項: Dove 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813459/
https://ncbi.nlm.nih.gov/pubmed/33469270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S289016
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