Bioequivalence and Pharmacokinetic Profiles of Generic and Branded Obeticholic Acid in Healthy Chinese Subjects Under Fasting and Fed Conditions

OBJECTIVES: This study was conducted to evaluate the bioequivalence (BE) of a generic form of obeticholic acid (OCA) and Ocaliva(TM) under fasting and fed conditions and to determine the effects of food on the pharmacokinetic (PK) profiles of OCA in healthy Chinese subjects. METHODS: A randomized, s...

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Bibliografiska uppgifter
I publikationen:Drug Des Devel Ther
Huvudupphovsmän: Wang, Meng-Na, Yu, Hai-Tao, Li, Ya-Qian, Zeng, Yun, Yang, Shuang, Yang, Guo-Ping, Pei, Qi, Huang, Jie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove 2021
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813459/
https://ncbi.nlm.nih.gov/pubmed/33469270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S289016
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