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Bioequivalence and Pharmacokinetic Profiles of Generic and Branded Obeticholic Acid in Healthy Chinese Subjects Under Fasting and Fed Conditions

OBJECTIVES: This study was conducted to evaluate the bioequivalence (BE) of a generic form of obeticholic acid (OCA) and Ocaliva(TM) under fasting and fed conditions and to determine the effects of food on the pharmacokinetic (PK) profiles of OCA in healthy Chinese subjects. METHODS: A randomized, s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Drug Des Devel Ther
मुख्य लेखकों: Wang, Meng-Na, Yu, Hai-Tao, Li, Ya-Qian, Zeng, Yun, Yang, Shuang, Yang, Guo-Ping, Pei, Qi, Huang, Jie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813459/
https://ncbi.nlm.nih.gov/pubmed/33469270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S289016
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