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Effects of alcohol on human carboxylesterase drug metabolism
BACKGROUND AND OBJECTIVE: Human carboxylesterase-1 (CES1) and human carboxylesterase-2 (CES2) play an important role in metabolizing many medications. Alcohol is a known inhibitor of these enzymes but the relative effect on CES1 and CES2 is unknown. The aim of this study is to determine the impact o...
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Publicado no: | Clin Pharmacokinet |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4450114/ https://ncbi.nlm.nih.gov/pubmed/25511794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-014-0226-2 |
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