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The role of human carboxylesterases in drug metabolism: have we overlooked their importance?

Carboxylesterases are a multi-gene family of enzymes widely distributed throughout the body of mammals that catalyze the hydrolysis of esters, amides, thioesters, and carbamates. In humans, two carboxylesterases, hCE1 and hCE2, are important pathways of drug metabolism. Both are expressed in the liv...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Pharmacotherapy
Asıl Yazarlar: Laizure, S. Casey, Herring, Vanessa, Hu, Zheyi, Witbrodt, Kevin, Parker, Robert B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572478/
https://ncbi.nlm.nih.gov/pubmed/23386599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1194
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