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Effects of alcohol on human carboxylesterase drug metabolism
BACKGROUND AND OBJECTIVE: Human carboxylesterase-1 (CES1) and human carboxylesterase-2 (CES2) play an important role in metabolizing many medications. Alcohol is a known inhibitor of these enzymes but the relative effect on CES1 and CES2 is unknown. The aim of this study is to determine the impact o...
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Veröffentlicht in: | Clin Pharmacokinet |
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Hauptverfasser: | , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2015
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4450114/ https://ncbi.nlm.nih.gov/pubmed/25511794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-014-0226-2 |
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