Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

ανά Alzubi, Jamal, Pallant, Celeste, Mussolino, Claudio, Howe, Steven J., Thrasher, Adrian J., Cathomen, Toni
Τόπος έκδοσης Sci Rep (2017)

Tolerance Induction Using Lentiviral Gene Delivery Delays Onset and Severity of Collagen II Arthritis

ανά Gjertsson, Inger, Laurie, Karen L, Devitt, James, Howe, Steven J, Thrasher, Adrian J, Holmdahl, Rikard, Gustafsson, Kenth
Έκδοση 2009

Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells

ανά Lambert, Jonathan R. A., Howe, Steven J., Rahim, Ahad A., Burke, Derek G., Heales, Simon J. R.
Τόπος έκδοσης Int J Mol Sci (2019)

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer

ανά Munye, Mustafa M., Tagalakis, Aristides D., Barnes, Josephine L., Brown, Rachel E., McAnulty, Robin J., Howe, Steven J., Hart, Stephen L.
Τόπος έκδοσης Sci Rep (2016)

Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cel...

ανά Zhang, Fang, Thornhill, Susannah I., Howe, Steven J., Ulaganathan, Meera, Schambach, Axel, Sinclair, Joanna, Kinnon, Christine, Gaspar, H. Bobby, Antoniou, Michael, Thrasher, Adrian J.
Έκδοση 2007

Perinatal Gene Transfer to the Liver

ανά McKay, Tristan R, Rahim, Ahad A, Buckley, Suzanne M.K, Ward, Natalie J, Chan, Jerry K.Y, Howe, Steven J, Waddington, Simon N
Έκδοση 2011

Evidence for Contribution of CD4+CD25+ Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery

ανά Nivsarkar, Megha S., Buckley, Suzanne M. K., Parker, Alan L., Perocheau, Dany, McKay, Tristan R., Rahim, Ahad A., Howe, Steven J., Waddington, Simon N.
Τόπος έκδοσης J Immunol Res (2015)

Gene Delivery of a Mutant TGFβ3 Reduces Markers of Scar Tissue Formation After Cutaneous Wounding

ανά Waddington, Simon N, Crossley, Rachel, Sheard, Vicky, Howe, Steven J, Buckley, Suzanne MK, Coughlan, Lynda, Gilham, David E, Hawkins, Robert E, McKay, Tristan R
Έκδοση 2010

The Landscape of Early Clinical Gene Therapies outside of Oncology

ανά Rittié, Laure, Athanasopoulos, Takis, Calero-Garcia, Miguel, Davies, Marie L., Dow, David J., Howe, Steven J., Morrison, Alastair, Ricciardelli, Ida, Saudemont, Aurore, Jespers, Laurent, Clay, Timothy M.
Τόπος έκδοσης Mol Ther (2019)

Lentiviral vectors can be used for full-length dystrophin gene therapy

ανά Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
Τόπος έκδοσης Sci Rep (2017)

Lentiviral vectors can be used for full-length dystrophin gene therapy

ανά Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
Τόπος έκδοσης Sci Rep (2017)

Erratum: Lentiviral vectors can be used for full-length dystrophin gene therapy

ανά Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
Τόπος έκδοσης Sci Rep (2017)

Self-inactivating Gammaretroviral Vectors for Gene Therapy of X-linked Severe Combined Immunodeficiency

ανά Thornhill, Susannah I, Schambach, Axel, Howe, Steven J, Ulaganathan, Meera, Grassman, Elke, Williams, David, Schiedlmeier, Bernhard, Sebire, Neil J, Gaspar, H Bobby, Kinnon, Christine, Baum, Christopher, Thrasher, Adrian J
Τόπος έκδοσης Mol Ther (2008)

BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity

ανά Munye, Mustafa M., Shoemark, Amelia, Hirst, Robert A., Delhove, Juliette M., Sharp, Tyson V., McKay, Tristan R., O’Callaghan, Christopher, Baines, Deborah L., Howe, Steven J., Hart, Stephen L.
Τόπος έκδοσης Am J Physiol Lung Cell Mol Physiol (2017)

Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors

ανά Alonso-Ferrero, Maria E., van Til, Niek P., Bartolovic, Kerol, Mata, Márcia F., Wagemaker, Gerard, Moulding, Dale, Williams, David A., Kinnon, Christine, Waddington, Simon N., Milsom, Michael D., Howe, Steven J.
Τόπος έκδοσης Exp Hematol (2018)

Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates

ανά Mattar, Citra N., Wong, Andrew M. S., Hoefer, Klemens, Alonso-Ferrero, Maria E., Buckley, Suzanne M. K., Howe, Steven J., Cooper, Jonathan D., Waddington, Simon N., Chan, Jerry K. Y., Rahim, Ahad A.
Τόπος έκδοσης FASEB J (2015)

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy

ανά Vink, Conrad A., Counsell, John R., Perocheau, Dany P., Karda, Rajvinder, Buckley, Suzanne M.K., Brugman, Martijn H., Galla, Melanie, Schambach, Axel, McKay, Tristan R., Waddington, Simon N., Howe, Steven J.
Τόπος έκδοσης Mol Ther (2017)

Hematopoietic Stem Cell and Gene Therapy Corrects Primary Neuropathology and Behavior in Mucopolysaccharidosis IIIA Mice

ανά Langford-Smith, Alexander, Wilkinson, Fiona L, Langford-Smith, Kia J, Holley, Rebecca J, Sergijenko, Ana, Howe, Steven J, Bennett, William R, Jones, Simon A, Wraith, JE, Merry, Catherine LR, Wynn, Robert F, Bigger, Brian W
Έκδοση 2012

In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters

ανά Buckley, Suzanne M. K., Delhove, Juliette M. K. M., Perocheau, Dany P., Karda, Rajvinder, Rahim, Ahad A., Howe, Steven J., Ward, Natalie J., Birrell, Mark A., Belvisi, Maria G., Arbuthnot, Patrick, Johnson, Mark R., Waddington, Simon N., McKay, Tristan R.
Τόπος έκδοσης Sci Rep (2015)

Lentiviral Vector Integration Profiles Differ in Rodent Postmitotic Tissues

ανά Bartholomae, Cynthia C, Arens, Anne, Balaggan, Kamaljit S, Yáñez-Muñoz, Rafael J, Montini, Eugenio, Howe, Steven J, Paruzynski, Anna, Korn, Bernhard, Appelt, Jens Uwe, MacNeil, Angus, Cesana, Daniela, Abel, Ulrich, Glimm, Hanno, Naldini, Luigi, Ali, Robin R, Thrasher, Adrian J, von Kalle, Christof, Schmidt, Manfred
Έκδοση 2011