Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity

Por Suerth, Julia D, Maetzig, Tobias, Brugman, Martijn H, Heinz, Niels, Appelt, Jens-Uwe, Kaufmann, Kerstin B, Schmidt, Manfred, Grez, Manuel, Modlich, Ute, Baum, Christopher, Schambach, Axel
Publicado em 2012

Bioinformatic Clonality Analysis of Next-Generation Sequencing-Derived Viral Vector Integration Sites

Por Arens, Anne, Appelt, Jens-Uwe, Bartholomae, Cynthia C., Gabriel, Richard, Paruzynski, Anna, Gustafson, Derek, Cartier, Nathalie, Aubourg, Patrick, Deichmann, Annette, Glimm, Hanno, von Kalle, Christof, Schmidt, Manfred
Publicado em 2012

High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies

Por Giordano, Frank A, Appelt, Jens-Uwe, Link, Barbara, Gerdes, Sebastian, Lehrer, Christina, Scholz, Simone, Paruzynski, Anna, Roeder, Ingo, Wenz, Frederik, Glimm, Hanno, von Kalle, Christof, Grez, Manuel, Schmidt, Manfred, Laufs, Stephanie
Publicado no Mol Ther Methods Clin Dev (2015)

Lentiviral Vector Integration Profiles Differ in Rodent Postmitotic Tissues

Por Bartholomae, Cynthia C, Arens, Anne, Balaggan, Kamaljit S, Yáñez-Muñoz, Rafael J, Montini, Eugenio, Howe, Steven J, Paruzynski, Anna, Korn, Bernhard, Appelt, Jens Uwe, MacNeil, Angus, Cesana, Daniela, Abel, Ulrich, Glimm, Hanno, Naldini, Luigi, Ali, Robin R, Thrasher, Adrian J, von Kalle, Christof, Schmidt, Manfred
Publicado em 2011

Stable Human FIX Expression After 0.9G Intrauterine Gene Transfer of Self-complementary Adeno-associated Viral Vector 5 and 8 in Macaques

Por Mattar, Citra NZ, Nathwani, Amit C, Waddington, Simon N, Dighe, Niraja, Kaeppel, Christine, Nowrouzi, Ali, Mcintosh, Jenny, Johana, Nuryanti B, Ogden, Bryan, Fisk, Nicholas M, Davidoff, Andrew M, David, Anna, Peebles, Donald, Valentine, Marcus B, Appelt, Jens-Uwe, von Kalle, Christof, Schmidt, Manfred, Biswas, Arijit, Choolani, Mahesh, Chan, Jerry KY
Publicado em 2011