Bioinformatic Clonality Analysis of Next-Generation Sequencing-Derived Viral Vector Integration Sites

Clonality analysis of viral vector-transduced cell populations represents a convincing approach to dissect the physiology of tissue and organ regeneration, to monitor the fate of individual gene-corrected cells in vivo, and to assess vector biosafety. With the decoding of mammalian genomes and the i...

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Detalhes bibliográficos
Main Authors: Arens, Anne, Appelt, Jens-Uwe, Bartholomae, Cynthia C., Gabriel, Richard, Paruzynski, Anna, Gustafson, Derek, Cartier, Nathalie, Aubourg, Patrick, Deichmann, Annette, Glimm, Hanno, von Kalle, Christof, Schmidt, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015219/
https://ncbi.nlm.nih.gov/pubmed/22559057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2011.219
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