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Analyzing the Number of Common Integration Sites of Viral Vectors – New Methods and Computer Programs

Vectors based on γ-retroviruses or lentiviruses have been shown to stably express therapeutical transgenes and effectively cure different hematological diseases. Molecular follow up of the insertional repertoire of gene corrected cells in patients and preclinical animal models revealed different int...

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Detalhes bibliográficos
Main Authors: Abel, Ulrich, Deichmann, Annette, Nowrouzi, Ali, Gabriel, Richard, Bartholomae, Cynthia C., Glimm, Hanno, von Kalle, Christof, Schmidt, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194800/
https://ncbi.nlm.nih.gov/pubmed/22022353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024247
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