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Analyzing the Number of Common Integration Sites of Viral Vectors – New Methods and Computer Programs

Vectors based on γ-retroviruses or lentiviruses have been shown to stably express therapeutical transgenes and effectively cure different hematological diseases. Molecular follow up of the insertional repertoire of gene corrected cells in patients and preclinical animal models revealed different int...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Abel, Ulrich, Deichmann, Annette, Nowrouzi, Ali, Gabriel, Richard, Bartholomae, Cynthia C., Glimm, Hanno, von Kalle, Christof, Schmidt, Manfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194800/
https://ncbi.nlm.nih.gov/pubmed/22022353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024247
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