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Stable Human FIX Expression After 0.9G Intrauterine Gene Transfer of Self-complementary Adeno-associated Viral Vector 5 and 8 in Macaques
Intrauterine gene transfer (IUGT) offers ontological advantages including immune naiveté mediating tolerance to the vector and transgenic products, and effecting a cure before development of irreversible pathology. Despite proof-of-principle in rodent models, expression efficacy with a therapeutic t...
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| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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Nature Publishing Group
2011
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222517/ https://ncbi.nlm.nih.gov/pubmed/21629224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.107 |
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