Immunologic Monitoring of Cellular Immune Responses in Cancer Vaccine Therapy

Por Whiteside, Theresa L., Gulley, James L., Clay, Timothy M., Tsang, Kwong Yok
Publicado em 2011

Adenovirus Infection Triggers a Rapid, MyD88-Regulated Transcriptome Response Critical to Acute-Phase and Adaptive Immune Responses In Vivo

Por Hartman, Zachary C., Kiang, Anne, Everett, Ruth S., Serra, Delila, Yang, Xiao Y., Clay, Timothy M., Amalfitano, Andrea
Publicado em 2007

Replication-attenuated Human Adenoviral Type 4 vectors elicit capsid dependent enhanced innate immune responses that are partially dependent upon interactions with the complement s...

Por Hartman, Zachary C., Appledorn, Daniel M., Serra, Delila, Glass, Oliver, Mendelson, Todd, Clay, Timothy M., Amalfitano, Andrea
Publicado em 2008

Release of endogenous danger signals from HIFU-treated tumor cells and their stimulatory effects on APCs

Por Hu, Zhenlin, Yang, Xiao Yi, Liu, Yunbo, Morse, Michael A., Lyerly, H. Kim, Clay, Timothy M., Zhong, Pei
Publicado em 2005

Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines

Por Morse, Michael A., Hobeika, Amy C., Osada, Takuya, Serra, Delila, Niedzwiecki, Donna, Lyerly, H. Kim, Clay, Timothy M.
Publicado em 2008

POLYCLONAL IMMUNE RESPONSES TO ANTIGENS ASSOCIATED WITH CANCER SIGNALING PATHWAYS AND NEW STRATEGIES TO ENHANCE CANCER VACCINES

Por Clay, Timothy M., Osada, Takuya, Hartman, Zachary C., Hobeika, Amy, Devi, Gayathri, Morse, Michael A., Lyerly, H. Kim
Publicado em 2011

Ligand-independent TLR signals generated by ectopic overexpression of MyD88 generate local and systemic anti-tumor immunity

Por Hartman, Zachary C., Osada, Takuya, Glass, Oliver, Yang, Xiao Y., Lei, Gang-jun, Lyerly, H. Kim, Clay, Timothy M.
Publicado em 2010

Immunodominant Liver-Specific Expression Suppresses Transgene-Directed Immune Responses in Murine Pompe Disease

Por Zhang, Ping, Sun, Baodong, Osada, Takuya, Rodriguiz, Ramona, Yang, Xiao Yi, Luo, Xiaoyan, Kemper, Alex R., Clay, Timothy M., Koeberl, Dwight D.
Publicado em 2012

HER2 overexpression elicits a pro-inflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis

Por Hartman, Zachary C., Yang, Xiao-Yi, Glass, Oliver, Lei, Gangjun, Osada, Takuya, Dave, Sandeep S., Morse, Michael A., Clay, Timothy M., Lyerly, Herbert Kim
Publicado em 2011

Investigation of HIFU-induced anti-tumor immunity in a murine tumor model

Por Hu, Zhenlin, Yang, Xiao Yi, Liu, Yunbo, Sankin, Georgy N, Pua, Eric C, Morse, Michael A, Lyerly, H Kim, Clay, Timothy M, Zhong, Pei
Publicado em 2007

Harmonization guidelines for HLA-peptide multimer assays derived from results of a large scale international proficiency panel of the Cancer Vaccine Consortium

Por Britten, Cedrik Michael, Janetzki, Sylvia, Ben-Porat, Leah, Clay, Timothy M., Kalos, Michael, Maecker, Holden, Odunsi, Kunle, Pride, Michael, Old, Lloyd, Hoos, Axel, Romero, Pedro
Publicado em 2009

Long term disease-free survival and T cell and antibody responses in women with high-risk Her2+ breast cancer following vaccination against Her2

Por Morse, Michael A, Hobeika, Amy, Osada, Takuya, Niedzwiecki, Donna, Marcom, Paul Kelly, Blackwell, Kimberly L, Anders, Carey, Devi, Gayathri R, Lyerly, H Kim, Clay, Timothy M
Publicado em 2007

Optimization of vaccine responses with an E1, E2b, E3 deleted Ad5 vector circumvents pre-existing anti-vector immunity

Por Osada, Takuya, Yang, Xiao Yi, Hartman, Zachary C., Glass, Oliver, Hodges, Bradley L., Niedzwiecki, Donna, Morse, Michael A., Lyerly, H. Kim, Amalfitano, Andrea, Clay, Timothy M.
Publicado em 2009

Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI)

Por Janetzki, Sylvia, Panageas, Katherine S., Ben-Porat, Leah, Boyer, Jean, Britten, Cedrik M., Clay, Timothy M., Kalos, Michael, Maecker, Holden T., Romero, Pedro, Yuan, Jianda, Martin Kast, W., Hoos, Axel
Publicado em 2007

Anti-helminth compound niclosamide downregulates Wnt Signaling and elicits antitumor responses in tumors with activating APC mutations

Por Osada, Takuya, Chen, Minyong, Yang, Xiao Yi, Spasojevic, Ivan, Vandeusen, Jeffrey B., Hsu, David, Clary, Bryan M., Clay, Timothy M., Chen, Wei, Morse, Michael A., Lyerly, H. Kim
Publicado em 2011

Immunomodulatory Gene Therapy Prevents Antibody Formation and Lethal Hypersensitivity Reactions in Murine Pompe Disease

Por Sun, Baodong, Kulis, Michael D, Young, Sarah P, Hobeika, Amy C, Li, Songtao, Bird, Andrew, Zhang, Haoyue, Li, Yifan, Clay, Timothy M, Burks, Wesley, Kishnani, Priya S, Koeberl, Dwight D
Publicado em 2009

An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer

Por Morse, Michael A., Hobeika, Amy C., Osada, Takuya, Berglund, Peter, Hubby, Bolyn, Negri, Sarah, Niedzwiecki, Donna, Devi, Gayathri R., Burnett, Bruce K., Clay, Timothy M., Smith, Jonathan, Lyerly, H. Kim
Publicado em 2010

Phase I clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibtion

Por Hamilton, Erika, Blackwell, Kimberly, Hobeika, Amy C, Clay, Timothy M, Broadwater, Gloria, Ren, Xiu-Rong, Chen, Wei, Castro, Henry, Lehmann, Frederic, Spector, Neil, Wei, Junping, Osada, Takuya, Lyerly, H Kim
Publicado em 2012

Co-delivery of antigen and IL-12 by Venezuelan equine encephalitis virus replicon particles enhances antigen-specific immune responses and antitumor effects

Por Osada, Takuya, Berglund, Peter, Morse, Michael A., Hubby, Bolyn, Lewis, Whitney, Niedzwiecki, Donna, Yang, Xiao Yi, Hobeika, Amy, Burnett, Bruce, Devi, Gayathri R., Clay, Timothy M., Smith, Jonathan, Kim Lyerly, H.
Publicado em 2012

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

Por Morse, Michael A, Garst, Jennifer, Osada, Takuya, Khan, Shubi, Hobeika, Amy, Clay, Timothy M, Valente, Nancy, Shreeniwas, Revati, Sutton, Mary Ann, Delcayre, Alain, Hsu, Di-Hwei, Le Pecq, Jean-Bernard, Lyerly, H Kim
Publicado em 2005