تحميل...
An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer
Therapeutic anticancer vaccines are designed to boost patients’ immune responses to tumors. One approach is to use a viral vector to deliver antigen to in situ DCs, which then activate tumor-specific T cell and antibody responses. However, vector-specific neutralizing antibodies and suppressive cell...
محفوظ في:
المؤلفون الرئيسيون: | , , , , , , , , , , , |
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التنسيق: | Artigo |
اللغة: | Inglês |
منشور في: |
American Society for Clinical Investigation
2010
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الموضوعات: | |
الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929723/ https://ncbi.nlm.nih.gov/pubmed/20679728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42672 |
الوسوم: |
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